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Re: How do I lower pro-inflammatory cytokines? » joe schmoe

Posted by Trotter on December 12, 2012, at 19:11:10

In reply to Re: How do I lower pro-inflammatory cytokines? » Trotter, posted by joe schmoe on December 12, 2012, at 17:19:44

Yes, he seems to have nothing nice to say about EPA at all. A bit biased I suspect.

I am going to take 1050mg EPA and 150mg DHA (7:1) for depression. Some 'experts' say to take up to 4g EPA for depression, but there is no evidence to support using more than 1g. In fact in the only study of dosages for depression, 1g EPA was more effective than 2g or 4g. Also, I've taken 4g EPA in the past and I didn't notice any profound change in my mood.

I think EPA is a weak antidepressant at best (DHA not at all). It is probably most helpful to augment other antidepressant medications, something it has been shown to do. I doubt it is dose responsive. I suspect any benefit is purely from addressing an EPA deficiency in the western diet.


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