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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 19 of 19. This is the beginning of the thread.
Posted by Tom Twilight on August 22, 2005, at 8:00:25
I was wondering if Naril is with or without food med?
Is it best absorbed on an empty stomach or with food?
Posted by Ilene on August 22, 2005, at 12:52:54
In reply to Nardil absorbtion and food, posted by Tom Twilight on August 22, 2005, at 8:00:25
> I was wondering if Naril is with or without food med?
> Is it best absorbed on an empty stomach or with food?This is what I found: "Avoid alcohol. Take drug at least 30 minutes before meal. "
You could try calling the drugstore where you got it, too.
I.
Posted by Declan on August 22, 2005, at 18:30:00
In reply to Re: Nardil absorbtion and food » Tom Twilight, posted by Ilene on August 22, 2005, at 12:52:54
Hey Tom
I was lying in bed this morning thinking about Nardil, as you do, and Plasmin Plus. You remember Michael Bell's post on that? Noone has been talking about that and problems with the new Nardil lately. But I wonder if there's something in it, ie that Nardil is best absorbed directly from the small intestine.
Noone's mentioned Nardil under the tongue.
Declan
Posted by Tom Twilight on August 23, 2005, at 6:44:16
In reply to Re: Nardil absorbtion and food, posted by Declan on August 22, 2005, at 18:30:00
I'm actually still on 40mg of Marplan, but I imagine that the absorbtion for Marplan must be similar to Nardil
The "under the tongue" suggestion is intrigueing
Posted by ed_uk on August 23, 2005, at 16:03:58
In reply to Re: Nardil absorbtion and food, posted by Declan on August 22, 2005, at 18:30:00
Hi Dec,
AFAIK, the Australian Nardil has different 'inactive ingredients' to the US Nardil. I think it's similar to the UK Nardil. I don't believe that there are any problems with it.
Kind regards
~Ed
Posted by Declan on August 23, 2005, at 22:22:47
In reply to Re: Nardil absorbtion and food » Declan, posted by ed_uk on August 23, 2005, at 16:03:58
Hi Ed
Is it just the US Nardil that's the problem? There have been a lot of posts about all this but I'm not really clear about it. Ace, at any rate, doesn't have any problems with the Australian version.
Declan
Posted by tecknohed on August 25, 2005, at 18:19:44
In reply to Nardil absorbtion and food, posted by Tom Twilight on August 22, 2005, at 8:00:25
> I was wondering if Naril is with or without food med?
> Is it best absorbed on an empty stomach or with food?Hey Tom.
I find that Nardil is actually 'delayed' when taken on an empty stomache.
For me its one of those meds which gives both short term benifits (ie, I feel an effect shortly after ingestion - like a benzo - maybe due to its GABA effects (?)) as well as the standard AD 'build-up' effect.
If I take it with/after food I feel its effects within an hour. But if I take it on an empty stomache, I tend not to feel much effect until I've eaten something, sometimes several hours later. I have NO idea why this is.
I know that with Moclobamide (Manerix etc) you need to take with food (again dont know why). With Marplan I felt it 'doing its thing' within the hour, whether I had eaten or not. Dispite both being MAOIs 'and' Hydrazine derivatives, I'm not so sure that Nardil and Marplan are really so similar.
Regards.
Posted by ed_uk on August 26, 2005, at 13:53:17
In reply to Re: Nardil absorbtion and food » Tom Twilight, posted by tecknohed on August 25, 2005, at 18:19:44
>If I take it with/after food I feel its effects within an hour. But if I take it on an empty stomache, I tend not to feel much effect until I've eaten something, sometimes several hours later. I have NO idea why this is.
AFAIK, the stomach empties more quickly when it's full of food. Perhaps that's why.
How did you find moclobemide? I tried it a while ago but it didn't do anything.
~ed
Posted by tecknohed on August 27, 2005, at 0:22:41
In reply to Re: Nardil absorbtion and food » tecknohed, posted by ed_uk on August 26, 2005, at 13:53:17
Tried moclobamide for a month at 600mg/day for Social Phobia. Hard to tell how effective it was. I remember I didnt go out alot so it wasn't motivating (apart from the 1st week). I didn't feel depressed before I took it so I dont know if it helped my mood or not, though it certainly didnt worsen it.
I stopped it because, after about 2 weeks I started falling asleep early evening after dinner. Didnt matter what I was doing - one minute I'd be alert, next I'd be nodding off. I HATE feeling sedated like this so I stopped it. A fear I developed from taking SSRIs, I think.
Posted by ed_uk on August 27, 2005, at 13:38:46
In reply to Re: Nardil absorbtion and food » ed_uk, posted by tecknohed on August 27, 2005, at 0:22:41
Does Nardil make you drowsy?
~Ed
Posted by tecknohed on August 27, 2005, at 17:17:06
In reply to Re: Nardil absorbtion and food » tecknohed, posted by ed_uk on August 27, 2005, at 13:38:46
> Does Nardil make you drowsy?
>
> ~EdNot quite drowsy, but it sedates. This seems to happen more the longer I take it. If I have something to do then I'm fine. However, put me on a train, in front of a TV or in a cinema (basically when I'm seated 'motionless') and it's ZZZZzzzzzzzzzz.........! The sedation is stronger if I've just taken a dose. My guess is its the GABA effect it has.
This is exactly what Moclobemide sedation was like , except with Nardil it can happen anytime, morning or night. With Moclobamide its mainly after the evening meal/dose.
Despite its sedation I take Nardil cause its the only thing thats ever touched my Social Phobia (and a lot more besides). Plus, the sedations not really unpleasant, just inconvenient.
Teck
Posted by ed_uk on August 28, 2005, at 7:58:49
In reply to Re: Nardil absorbtion and food » ed_uk, posted by tecknohed on August 27, 2005, at 17:17:06
Hi Kev,
>This seems to happen more the longer I take it. If I have something to do then I'm fine. However, put me on a train, in front of a TV or in a cinema (basically when I'm seated 'motionless') and it's ZZZZzzzzzzzzzz.........!
That's rather what SSRIs are like for me!
Kind regards
~Ed
Posted by tecknohed on August 28, 2005, at 13:35:42
In reply to Re: Nardil absorbtion and food » tecknohed, posted by ed_uk on August 28, 2005, at 7:58:49
SSRIs not only make me tired but they cause me fatigue, stimulant craving, somnolence and extreme hypersomnia (excessive over sleeping).
SSRIs - YUCK! (personal opinion of course)
Posted by ed_uk on August 28, 2005, at 14:32:17
In reply to Re: Nardil absorbtion and food » ed_uk, posted by tecknohed on August 28, 2005, at 13:35:42
>SSRIs - YUCK!
I don't really like them but they do help my OCD :-S
Kind regards
~Ed
Posted by ed_uk on August 28, 2005, at 14:33:30
In reply to Re: Nardil absorbtion and food » ed_uk, posted by tecknohed on August 28, 2005, at 13:35:42
>SSRIs not only make me tired but they cause me fatigue, stimulant craving, somnolence and extreme hypersomnia (excessive over sleeping).
PS. Which SSRIs did you try? Did any of them cause less of the above-mentioned side effects?
~ed
Posted by tecknohed on August 29, 2005, at 4:48:35
In reply to Re: Nardil absorbtion and food » tecknohed, posted by ed_uk on August 28, 2005, at 14:33:30
> >SSRIs not only make me tired but they cause me fatigue, stimulant craving, somnolence and extreme hypersomnia (excessive over sleeping).
>
> PS. Which SSRIs did you try? Did any of them cause less of the above-mentioned side effects?
>
> ~edFluoxetine (Prozac) did cause less fatigue, etc but I still ended up a bit lethargic. It's certainly the least problem-causing SSRI I've taken. Sertraline (Lustral, Zoloft) made me feel just 'wierd'. It also caused less lethargy but it gave me vivid/bad dreams, and 'strange' thoughts. Not great for my SP iether.
I've tried all other SSRIs except fluvoxamine. Anything 'primarily' serotonergic is a no-no for me. Also tried venlafaxine, nefazodone, and clomipramine, all with basically a similar 'slow down' result.
I find it bizarre how paroxetine is often a first line treatment for SP and yet 'everyone' I've known on it not only get lethergic, but niether does it help thier SP much. I guess that when thier doctors ask how they are, they often say "well I am CALMER (surprise surprise)". But if they asked them specifically how thier SP was (which they never semm to do), I think they would get a much different responce! And it annoys me when they put the lethargy down to the 'depression'.
Still, my girlfriend takes Prozac for her moods and SP and is doing well (she also got lethargic on paroxetine). Each to thier own I guess.
Posted by ed_uk on August 29, 2005, at 5:30:35
In reply to Re: Nardil absorbtion and food, posted by tecknohed on August 29, 2005, at 4:48:35
Hi Kev!
Out of the SSRIs, I've tried citalopram up to 80mg, paroxetine up to 60mg and fluoxetine 20mg. I've also tried venlafaxine. Paroxetine caused considerable drowsiness and lethargy. I'm thinking of trying sertraline or fluoxetine at a higher dose.
>It also caused less lethargy but it gave me vivid/bad dreams, and 'strange' thoughts.
What sort of thoughts?
How did you find citalopram and escitalopram btw?
>And it annoys me when they put the lethargy down to the 'depression'.
Me too. I wasn't depressed on paroxetine, but I *was* too drowsy and apathetic to do anything.
Kind regards
~Ed
Posted by ed_uk on August 29, 2005, at 5:30:48
In reply to Re: Nardil absorbtion and food, posted by tecknohed on August 29, 2005, at 4:48:35
Hi Kev!
Out of the SSRIs, I've tried citalopram up to 80mg, paroxetine up to 60mg and fluoxetine 20mg. I've also tried venlafaxine. Paroxetine caused considerable drowsiness and lethargy. I'm thinking of trying sertraline or fluoxetine at a higher dose.
>It also caused less lethargy but it gave me vivid/bad dreams, and 'strange' thoughts.
What sort of thoughts?
How did you find citalopram and escitalopram btw?
>And it annoys me when they put the lethargy down to the 'depression'.
Me too. I wasn't depressed on paroxetine, but I *was* too drowsy and apathetic to do anything.
Kind regards
~Ed
Posted by Chairman_MAO on August 30, 2005, at 10:22:01
In reply to Nardil absorbtion and food, posted by Tom Twilight on August 22, 2005, at 8:00:25
I don't think food makes a significant difference.
If for some reason you want to increase your Nardil absorption, I feel bioperine (piperine) @ 10mg per dose does this very well. When I tried that, I could tell I was getting more into my system because I started getting really tired.
This is the end of the thread.
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