Posted by SLS on September 22, 2006, at 8:32:44
In reply to Need Benzo Stabilization B4 Attempt Narc Withdraw, posted by corafree on September 22, 2006, at 2:01:45
Hi CF.
> Have you ever had 'a lesser dosage' of a med work better for you than 'a higher dosage'? If so, what kind, and do you know why?Yes. Nortriptyline is known to have what is known as a "therapeutic window", which is a narrow range of dosages that a drug is effective. Too low or too high, and it doesn't work. I don't think anyone knows why.
> Also, could a person develop 'a high tolerance' to all medication in general? If so, would a different way of administration be helpful?I think people can become "cross-tolerant" to medications of a class in which all of the drugs work the same way. However, there are many examples of people failing to respond to one SSRI and going on to respond to another. Sometimes, you can recapture a drug response by discontinuing it and waiting some length of time and restarting it. Another option is to augment the drug with another drug.
> I was taking Lyrica 75mg h.s. & 'feeling emotionally good' plus 'not desperately craving 2nd daily dose oxycodone'. When increased to 150mg h.s. tho', felt uncomfortable emotionally and physically.
Ok.
> (That's when I wrote the, too long, rambling, freakin' life story of a post! OMG, that was ridiculous! Poor Holly. Sorry Holly! My posts aren't always like that. Don't blame U for not reading S. Don't be scared Holly to write to me Holly; I won't do it again.)
Please don't apologize for the length of your post. Just because I have difficulties reading due to my illness shouldn't cause you to change your posting behavior.
> I'll give Lyrica dosage increase another shot when not on stress overload.
I'm planning to move up to 600mg at some point. I just started 450mg.
I wonder if you could cross over to buprenorphine and then taper that. This is an effective treatment for heroin addiction.
- Scott
poster:SLS
thread:684185
URL: http://www.dr-bob.org/babble/wdrawl/20060809/msgs/688130.html