Posted by TriedEveryMedication on April 17, 2011, at 23:04:10
The Viibryd PI is out.
(http://www.frx.com/pi/viibryd_pi.pdf)
Was looking at the efficacy. Seems to be 2.5 to 3.2 points more reduction in depression after 8 weeks than the placebo (MADRS scale).Lexapro seems to be about 5 or 6 MADRS clicks lower than placebo after 8 weeks from what I have read.
That does not sound too good. I had some hopes for this newest iDrug and was getting ready to camp out in front of walgreens on launch day.
Maybe not :D
Here's the info on the sides, vs. placebo:
.................VIIBRYD(436).....Placebo(433)
Gastrointestinal disorders
Diarrhea.............28.............9
Nausea...............23.............5
Dry mouth.............8.............5
Vomiting..............5.............1
Dyspepsia.............3.............2
Flatulence............3.............2
Gastroenteritis.......3............<1
Nervous system disorders
Dizziness.............9.............5
Somnolence............3.............2
Paresthesia...........3.............1
Tremor................2.............0
Psychiatric disorders
Insomnia..............6.............2
Abnormal dreams.......4.............1
Libido decreased......4............<1
Restlessness *........3............<1
Orgasm abnormal.......3.............0
General disorders
Fatigue...............4.............3
Feeling jittery.......2............<1
Cardiac disorders
Palpitations..........2............<1
Musculoskeletal and connective tissue disorders
Arthralgia............3.............2
Reproductive system and breast disorders
Delayed ejaculation...2.............0
Erectile dysfunction..2.............1
Metabolism and nutrition disorders
Increased appetite....2.............1
poster:TriedEveryMedication
thread:983120
URL: http://www.dr-bob.org/babble/20110406/msgs/983120.html