Posted by Vincent_QC on March 7, 2009, at 15:38:21
In reply to Re: Clomipramine (Someone else take that AD now) ??? » Vincent_QC, posted by Incubusfan on March 6, 2009, at 22:39:51
> I've also switched from a trial of Clomipramine to a trial of Noritriptyline.
>
> 20MG of Noritriptyline so far has caused basically no side effects vs 25mg of Clomipramine which would made me fatigued, tired, lethargic, high heart rate, etc. My doctor wants me to test low doses to see if I tolerate this better.
>
> Good luck.Hi !
Wow, that's so weird how a med act on a person to another person. I encounter the opposite effect. The Clomipramine at 50mg was more easy for me than a small 20mg dose of Nortryptiline. The Clomipramine make me mentally tired, but I didn't had a lot of side-effects (except goosebumps and sedation) but no side-effect on my blood pressure and heart rate and after 3 weeks, no improve on my SAD or GAD or depression...nothing...I take the decision to Stop the Nortryptiline after I take my last 10mg dose at noon today. My heart pluse go up to 165, I was out of breath for almost 2 hours...that's very not good for the panic disorder and for the GAD as well...now, after 4 hours my pulse rate is around 125...still very high...and I got this strange headache and sensation on my left temple...I hate that!!!
That's seem that I don't tolerate well the NE effect of the Nortryptiline...so the guy who was talking about the reuptake of NE and the worsing effect on the SAD was right I suppose... I prefer the inhibition of the NE cause by the MAOI's...at least, they don'T make me fell like my heart will explose because he beat too fast...but I still get hypertensives crisis on them as well as hypotension orthostatic...semm like regular side-effects on everyone who use them...
I will have to call my PDoc monday morning and maybe ask to stop everything for at least 14 days and be back again on a low dose of Parnate, the only thing that have an immediate effect on my SAD...but also giving me some hypertension problem...the 20mg dose will be probably the target for me...that's better than nothing... Or maybe switch to the Surmontil (Trimipramine) who seem to be more sedative but more good for the anxiety...ans less hard for the heart...
Well good luck with the Nortryptiline, I hope everything will be ok for you!!!
Take care!
Vincent ;-)
poster:Vincent_QC
thread:882809
URL: http://www.dr-bob.org/babble/20090304/msgs/884276.html