Posted by Vincent_QC on March 4, 2009, at 15:39:16
In reply to Re: Clomipramine (Someone else take that AD now) ??? » Vincent_QC, posted by myco on March 3, 2009, at 23:38:16
> Hey Vince,
>
> How is the battle to import Marplan into Canada going? I'm waiting to find out what happens as I'm also interested in this med.
>
> thnx
> Myco
Hi Myco!
Well, you ask the question at the good time...I had an appointment this afternoon with my PDoc, since I stop the Clomipramine (2 days ago) cause I wasn't able to tolerate the side-effects (Worsing social anxiety and general anxiety and also a strange sensation of pins and needles all over my body and partuculary on my head...like I was listening to a music that I like a lot...I had this strange sentation always...)... Anyway, I had my results for my blood test, everything is fine, even my TSH (T3 and T4) and my anemia problem seem to resolve itself with the treatments of intravenaous iron (Venofer) I recieve each month, so now the anemia problem seem to not be the cause of my worsing problem of tiredness and fatigue at daytime...I can't do anything at daytime cause I feel so exhausted and tired that I just want to stay in my bed, lying and watch the ceiling...well I don'T answer to your question...lol (Next paragraph)...lol
I ask the PDoc about the Marplan process and if he recieve an answer from Health Canada... and the answer is no... I was not surprise anyway...The PDoc say it can take more than 2 or 3 months before I recieve an answer... One of the Pharmacist at the psychiatric hospital where I go communicate often with Health Canada to see how the things involve...but my folder is not already study by them...I'm in a kind of waiting list...
For now, the PDoc told me that if I wasnt able to tolerate the Clomipramine (one of the most powerfull serotonin reuptake, more than the newer IRSS), he said that my Serotonin is probably not implicated in my SAD or GAD problems...That's not new...I always told him and the others PDoc I had that the meds who hit hard the Serotonin always dicrease my mental state...
Since I had a gastric by-pass in 2001 and that I can't absorb the newer extends releases like the Effexor-XR or Cymbalta.... I never really try a med who work on the NE so it's why the PDoc agree to put me on the Nortriptyline, that's not a dual action med like the Effexor or the Cymbalta (SE + Ne), but at least, we will be able to see if i'm anwsering well to the NE...
The good news is that with the Nortriptyline, I will be able to have a blood test to see the level of the drug I can absorb... when I will be stable on the good dose...after the last increase of the dosage, I will have to wait 2 weeks before the blood test...
For the first time since I had my gastric by-pass, I will be able to see if my gastric by-pass have a bad effect on the absorbation of the meds I take... The by-pass I had work with a malabsorbtion process, means that I have only 1 meter of intestine who work now...the other part is cut and don't work anymore...it's why I take huge amount of Vitamins and iron each day...that's completly different from the very popular by-pass they do in the USA, that one is only restrictive...
Well that's all... I begin the Nortryptiline at 20mg/day first week, increase at 50mg week two, and 75mg week three...I can reach a maximum dose of 200mg if I can tolerate the drug well and if it's effective for my SAD, GAD, panic disorder and depression problems...
I will give more news about the Marplan after my next appointment in April...for now it's on the studying processing...
I have nothing to loose to try others meds until I got an answer from Health Canada...maybe I will finally find something who work on me... The SAD and GAD problem with depression is so hard to treat and so many neurotransmettors are implicated into these problems and it's also different for everyone, it's hard to predict the action of a drug on someone...especially on me, with that gastric by-pass...If I was aware of the complications I got from this surgery, I Will never had it done on me... but that's to late, yes i'm not affected now with a morbid obesity problem now, but I have a lot of physicals pain as well as a hernia that's have to be repair for the third times...as well as a lot of plastic surgery to remove the extra skin I have all over my body, but I don't work and I can't afford it for now, maybe I will stay all the rest of my life with a body that I hate...and that nobody else will be able to like also... anyway, that's another problem... no wonder why I have also a BDD problem (Body dismorphic disorder)... Maybe i'm just crazy...who know...
Can I ask you a question??? For now, what are you using as a med??? Is it you that was suppose to begin the Nortyptiline 2 weeks ago? I have a poor memory and I remember that I read that on the board, but I can'T remember if it was a message from you or not??? IF it's you, did you find the Nortyptiline effective and did you have a lot of side-effects???
Well, that'S all...take care of you Myco ...and BTW...id you find a solution for the insomnia??? My Seroquel dosage begin to loose a lot of his powerfull action on me...the 50mg don't make me sleep more than 4 hours in a row...before I was sleeping more than 6 hours, sometimes more than 8 hours in a row without even wake-up 1 time to go to the bathroom in the middle of the night... Maybe it was related to the Clomipramine also, because I was dreaming a lot on it...more than usual...vivid dreams...
Another time, take care of you ok ;-)
Bye!
Vincent ;-)
poster:Vincent_QC
thread:882809
URL: http://www.dr-bob.org/babble/20090304/msgs/883763.html