Posted by Neurogen on February 7, 2009, at 8:59:04
Hello,
I orginally got on Nardil for SP and dysthymia/depression a year ago. I quickly titrated up to 75mg/day over a span of 4days or so. It was my 1mg/kg target. Sideeffects were minimal. By the end of the first week, I was feeling the drug good. Everytime I took a pill, within minutes I would get this soothing GABA buzz in my brain. My SA was completely wiped out. Depression was history. I felt free for the first time in my life. I stayed on the Nardil for approx. 1.5mo, about have that time taking 60mg or less.
I felt my brain was fixed, didnt want to pay expensive psych for more.I begin smoking pot again, excessively. I then experienced a major financial loss, which led to my cessation of the pot, and major lifestyle changes. My stress level slowly rose up, and I could literally feel my frontal lobe shutting down, becoming cloudy and atrophied.. Depression taking over. My SA came back strong and it brought some lovely Obsessional OCD with it.
I went into a severe melancholic depression. Worst episode I'd ever had. I had been on Nardil 60mg for 2weeks as I spiraled deeper. It was doing nothing at all, which had me confused and more depressed. I checked into the hospital, desperate, and having suicidal thoughts. I got them to increase dose to 75mg. Discharged after a week. Suicidal thoughts were leaving, but I was still very messed up. It's been a slow climb to remission.
Was at 60mg 2weeks, nothing.
Was at 75mg for about 10 weeks. Big improvement from beginning, but still depressed/anxiety problems .
Raise to 90mg for 6weeks, more improvement, depression nearly gone, anxiety lingers.
Raise to 105mg.
2.5 weeks in, slight improvement on anxiety.I don't like being on such a high dose. Sex is messed up, constipation annoying. They'll subside in time, but im tired of it.
I've now gained 20pounds over my initial weight.
I'm about 86kg and its coming down through exercise/diet.I augment with Klonopin .5/1mg sometimes when I want to zap the SA away.
So I wonder.. My mental conditions were very different both times on the drug. But I've been on Nardil now for about 4months at high dosages and it's acting like it's half-cocked.
It was like my first trial was with this different magical drug.Now what?..how to recapture full Nardil. Monotherapy prefferred.
Is there a therapeutic window I missed? Too much MAO inhibition? Lower dosage?
Drug holiday? Restart in a month.
Go Parnate?
poster:Neurogen
thread:878697
URL: http://www.dr-bob.org/babble/20090203/msgs/878697.html