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Re: Mood Stablizer with ZERO serotonin effect?

Posted by linkadge on June 10, 2008, at 7:32:40

In reply to Re: Mood Stablizer with ZERO serotonin effect?, posted by SLS on June 10, 2008, at 5:59:59

>This in turn increases dopamine release in the >nucleus accumbens, the reward, pleasure, and >motivational center in the limbic system

Is this true? The only reason I ask is because lamotrigine has dopamine depleting activity in certain brain regions.

http://www.medscape.com/viewarticle/418015_3

In support of conclusions regarding our patient, lamotrigine exerted prodystonic effects in Syrian hamsters with primary generalized dystonia.[22] It also reduced dopamine synthesis in the striatum of mice.[23]

Linkadge


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poster:linkadge thread:833737
URL: http://www.dr-bob.org/babble/20080606/msgs/833933.html