Posted by SLS on June 10, 2008, at 5:59:59
In reply to Re: Mood Stablizer with ZERO serotonin effect?, posted by Horned One on June 9, 2008, at 10:46:51
Hi.
Lamictal probably exerts its antidepressant effects via a reduction in the amount of glutamate released in the thalamus. This in turn increases dopamine release in the nucleus accumbens, the reward, pleasure, and motivational center in the limbic system. To the best of my knowledge, there is no direct or indirect effect of Lamictal on serotonin pathways.
- Scott
poster:SLS
thread:833737
URL: http://www.dr-bob.org/babble/20080606/msgs/833919.html