Posted by Tony P on February 19, 2004, at 3:29:02
In reply to Re: Buspar alone work for GAD for anyone?SSRI, posted by zeugma on February 18, 2004, at 18:49:14
In my experience, Buspar doesn't help that much with GAD, but people's response to it seems to vary greatly. By itself, the first time I tried it, it made me uncomfortably aggressive (my driving got really bad ;-), but then I was also withdrawing from benzos. The manufacturer of Buspar recommends NOT overlapping those two, precisely BECAUSE the Buspar doesn't have the GABA-mediated GAD relief/muscle relaxant effect that people are used to from benzodiazepines, so they naturally assume it isn't working.
Having said that, I got really GOOD results for several years with Serzone plus Buspar - Serzone coped with my endogenous depression, had a slight anxiolytic effect and really improved my sleep; Buspar stopped my stress/rage/depression vicious cycle as well as boosting the antidepressant effect. I've used it successfully at 20-30mg/day with _very_ low doses of Serzone (100-200 mg/day). My guess is it would help with the stress/rage response by itself for _some_ people. YMMV, as usual.
Tony P
poster:Tony P
thread:314724
URL: http://www.dr-bob.org/babble/20040218/msgs/315499.html