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Re: WARNING: hardcore technical moclobemide question

Posted by djmmm on May 7, 2002, at 19:12:50

In reply to WARNING: hardcore technical moclobemide question, posted by Will_Hung on May 7, 2002, at 17:12:21

At 750mg, the concentrations tend to go up and the half-life increases too. The half life is about 2 hours for the minimum dose.

the pharmacokinetics of a MAOI are a bit different than typical Antidepressants, because MAOI activity isn't necessarily correlated with half-life..in other words, MAO-A inhibition lasts much longer than the half-life of the actual drug, (probably about 20 or more hours)


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