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Buspar - "partial" agonist?

Posted by Scott L. Schofield on November 17, 1999, at 11:42:07

I often see buspirone (Buspar) described as being a "partial" agonist at 5-HT1a receptor sites.

1. What does "partial" mean?
(pre-synaptic vs post-synaptic?)

2. As an agonist, wouldn't it work against the antagonist activity of pindolol?


Thanks.

Scott


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poster:Scott L. Schofield thread:15384
URL: http://www.dr-bob.org/babble/19991108/msgs/15384.html