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Dr. Bob is Robert Hsiung, MD,
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Posted by linkadge on November 2, 2013, at 19:06:59
Has anyone had loss of efficacy of one benzodiazapine to have another (at an equivalent dose) work?
Linkadge
Posted by Phillipa on November 2, 2013, at 23:49:28
In reply to Is benzo cross tollerance inevitable?, posted by linkadge on November 2, 2013, at 19:06:59
I was told by a doctor at one time that this would work. Phillipa
Posted by Christ_empowered on November 3, 2013, at 10:15:46
In reply to Re: Is benzo cross tollerance inevitable? » linkadge, posted by Phillipa on November 2, 2013, at 23:49:28
Minimal experience with it myself, except with sleeping pills. Restoril--even the lower dose, 15mgs--worked better than high dose sonata or ambien. Those z hypnotics aren't technically benzos, but they're benzo-ish enough to be converted into diazepam equivalents, apparently.
Anyway, even though benzos are similar, there are differences. 2mgs/Klonopin=40mgs/diazepam, true, but what if the diazepam works better because of its unique profile (increased muscle relaxant properties, more sedation, etc.) ?
Then there's trying to get people on old school Xanax stabilized on something else. Probably a good idea. Even if the equivalent dose is the same, you should probably have less inter-dose anxiety and less dosage escalation...that's a good thing.
Personally, I did find that multi-doses of Ativan worked better than 2 doses Klonopin. Hits faster, doesn't last all day, less mood dampening.
Don't give up hope! Keep in mind that its kind of like switching antipsycohtics. Yes, x mgs/Zyprexa technically= x mgs/any number of other drugs, but they're still **different drugs**, so YMMV, right?
This is the end of the thread.
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