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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 8 of 8. This is the beginning of the thread.
Posted by Zyprexa on October 19, 2011, at 11:05:55
My doc just lowered the 15mg zyprexa down to 5mg starting tonight. I was at 10mg for a couple weeks and didn't see any difference from the 15mg. So now its going to be 5mg... Wish me luck! Hope theres no problems. Looks like the anxiety is coming from wellbutrin. So since the wellbutrin is reduced down to 100mg now, I shouldn't get anxiety. I also taking 12mg x3 perphenazine. Hoping to drop zyprexa and wellbutrin. But if this does not work guess I will have to take them..
Posted by Christ_empowered on October 19, 2011, at 16:00:41
In reply to Lowering zyprexa!!!, posted by Zyprexa on October 19, 2011, at 11:05:55
I hope this works out for you. Its always best to take 1 antipsychotic at the lowest effective dose instead of 2+ neuroleptics and then additional meds on top of that. I bet you'll feel clear headed and more "with it." Just a guess--I'm not a doc--but that's how dosage reductions and eliminating medications always makes me feel.
Posted by Phillipa on October 19, 2011, at 16:45:34
In reply to Great news!, posted by Christ_empowered on October 19, 2011, at 16:00:41
Zyprexa tha is indeed good news!!!! I'm betting it works for you!!!! Phillipa
Posted by SLS on October 19, 2011, at 17:24:19
In reply to Great news!, posted by Christ_empowered on October 19, 2011, at 16:00:41
> Its always best to take 1 antipsychotic at the lowest effective dose instead of 2+ neuroleptics
This is still a topic of debate.
There are studies that agree with your statement here. I am not sure that this is always true, though. I know one person who does well on Risperdal and Seroquel. If you take the Risperdal away, she becomes paranoid and psychotic. If you take away the Seroquel, depression and negative symptoms appear. I guess it is possible that substituting a drug like desipramine for the Seroquel would work, too. The bottom line is that there is not yet sufficient study of this issue to be able to prescribe a monolithic policy.
Each of these neuroleptic drugs differ in the properties they possess. Sometimes, you can't hit all of the necessary targets with one drug because no one drug possess all of the properties that neuroleptics as a group display collectively. Of course, this is all theoretical stuff, but it allows for a rationale for a proof-of-principle in considering polypharmacy as a treatment.
Should using multiple antidepressants be rejected as a viable treatment for MDD?
- Scott
Posted by SLS on October 19, 2011, at 17:33:15
In reply to Lowering zyprexa!!!, posted by Zyprexa on October 19, 2011, at 11:05:55
> My doc just lowered the 15mg zyprexa down to 5mg starting tonight. I was at 10mg for a couple weeks and didn't see any difference from the 15mg. So now its going to be 5mg... Wish me luck! Hope theres no problems. Looks like the anxiety is coming from wellbutrin. So since the wellbutrin is reduced down to 100mg now, I shouldn't get anxiety. I also taking 12mg x3 perphenazine. Hoping to drop zyprexa and wellbutrin. But if this does not work guess I will have to take them..
I would want to get rid of these drugs, too. Who wants to take psychiatric drugs?
I think taking away the Zyprexa and leaving the perphenazine makes a great deal of sense. It might be possible to use nortriptyline in place of Zyprexa if 5-HT2a antagonism is a necessary action in your treatment.
Good luck with your experimentation.
- Scott
Posted by Jeroen on October 20, 2011, at 12:15:47
In reply to Lowering zyprexa!!!, posted by Zyprexa on October 19, 2011, at 11:05:55
i think Saphris is available in my country now... not 100% sure
Posted by Zyprexa on October 21, 2011, at 5:34:22
In reply to Lowering zyprexa!!!, posted by Zyprexa on October 19, 2011, at 11:05:55
So far so good! See how work goes tonight.
Posted by Zyprexa on October 21, 2011, at 5:38:07
In reply to to Zyprexa, posted by Jeroen on October 20, 2011, at 12:15:47
Are you going to take it? It seems to be out here. They have a website. I'm still taking perphenazine with good results. So I'm going to stick with that.
This is the end of the thread.
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