Psycho-Babble Medication Thread 793685

Shown: posts 1 to 8 of 8. This is the beginning of the thread.

 

Wellbutrin XL - When to take it?

Posted by AnneL on November 6, 2007, at 21:33:45

I am going to give Wellbutrin XL 150 mg. a try.

If Wellbutrin XL is a once a day pill (24 hours) does it need to be taken in the AM to prevent insomnia?

Thanks in advance. :) AnneL

 

Re: Wellbutrin XL - When to take it? » AnneL

Posted by Phillipa on November 6, 2007, at 21:55:26

In reply to Wellbutrin XL - When to take it?, posted by AnneL on November 6, 2007, at 21:33:45

In my opinion and experience with it am. Phillipa

 

Re: Wellbutrin XL - When to take it?

Posted by oldschool305 on November 7, 2007, at 7:58:11

In reply to Re: Wellbutrin XL - When to take it? » AnneL, posted by Phillipa on November 6, 2007, at 21:55:26

definately take it in the AM. It's time released but by bedtime the strongest effects should have worn off. Unforunately, you may still have some trouble getting to sleep. Are you taking anything else with it? Hopefully something you can take at night just to be sure you get some sleep. I was taking Wellbutrin in the morning, and Lexapro at night which helped me fall asleep.

 

Re: Wellbutrin XL - When to take it? » oldschool305

Posted by AnneL on November 7, 2007, at 10:05:39

In reply to Re: Wellbutrin XL - When to take it?, posted by oldschool305 on November 7, 2007, at 7:58:11

I started the Wellbutrin XL 150 mg. this AM. I don't think I will have any problems falling asleep because I am taking 500 mg. of Depakote at bedtime along with Seroquel 50 mg, Rozerem 8 mg, and Klonopin 1 mg. I fall asleep and stay asleep for a good 9 hours!

I am really hoping that I can tolerate the Wellbutrin XL because I would like to finally get off of Effexor which is horrible due to sexual side effects. I am scared of all of the reports of nervousness, jitteriness,etc.

Thanks for your reply. :) AnneL

 

Re: Wellbutrin XL - When to take it?

Posted by simcha on November 9, 2007, at 14:23:14

In reply to Re: Wellbutrin XL - When to take it? » oldschool305, posted by AnneL on November 7, 2007, at 10:05:39

I take it at night. Somehow it seems to give me a burst of energy 8 to 10 hours after taking it. So, if I take it in the morning I seem to have worse insomnia at night. Perhaps I'm just a little odd...

 

Re: Wellbutrin XL - When to take it? » simcha

Posted by kaleidoscope on November 9, 2007, at 17:24:02

In reply to Re: Wellbutrin XL - When to take it?, posted by simcha on November 9, 2007, at 14:23:14

Hi Simcha

>I take it at night. Somehow it seems to give me a burst of energy 8 to 10 hours after taking it. So, if I take it in the morning I seem to have worse insomnia at night. Perhaps I'm just a little odd...

I don't think you are odd :) After taking a dose of Wellbutrin XL, the peak blood level generally occurs after about 5 hours, although this is variable of course. Taking it last thing at night will minimise the blood level at bedtime and maximise the blood level in the early morning. For this reason, taking it at bedtime may indeed be useful.

Taking Wellbutrin XL in the morning is more common, and is recommended by the manufacturer, but it may not be optimal for everyone.

Ed

 

Re: Wellbutrin XL - When to take it?

Posted by Zyprexa on November 12, 2007, at 13:10:06

In reply to Wellbutrin XL - When to take it?, posted by AnneL on November 6, 2007, at 21:33:45

I would take it all at breakfast time, first thing in morning. It will wake you up and last most of the day. Wearing off at night.

 

Wellbutrin depends on its active metabolites.

Posted by Astounder on November 15, 2007, at 20:51:30

In reply to Wellbutrin XL - When to take it?, posted by AnneL on November 6, 2007, at 21:33:45

> I am going to give Wellbutrin XL 150 mg. a try.
>
> If Wellbutrin XL is a once a day pill (24 hours) does it need to be taken in the AM to prevent insomnia?
>
> Thanks in advance. :) AnneL


All of which have long (24+ hr) half-lives and accumulate heavily. After a week or two, you'll be at a steady state and it shouldn't matter when you take.


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