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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 7 of 7. This is the beginning of the thread.
Posted by gargoyle on March 10, 2007, at 15:51:48
Hi All! need some info about patch. Went on parnate in 1981 (for ptsd/depression) as it was about all that was available then. Tried numerous new meds as they came available with various degrees of disaster including suidical acts. Finally back to parnate around 2003 and holding my own against suicide since then but still not "well" and hoping to improve. Anyone know if selegiline patch impacts on serotonin, norepinephrine and dopamine similar to parnate. Don't want to risk backslide but extremely tired of being "half alive" and hopeful. Seeing new doctor in a couple weeks since we recently relocated and want as much info to pass on as possible. Thanks for any help!!!!!
Posted by UgottaHaveHope on March 10, 2007, at 22:54:22
In reply to selegiline patch, posted by gargoyle on March 10, 2007, at 15:51:48
Every med affects everybody differently, but I would say the general consensus in here is that Parnate is stronger than Emsam.
Perhaps you could increase your dose of Parnate like many other have? Or switch to Nardil? Or combine Parnate with a TCA (look up SLS old posts).
Please keep us updated. Michael
Posted by gargoyle on March 11, 2007, at 11:20:05
In reply to Parnate or Emsam Stronger? » gargoyle, posted by UgottaHaveHope on March 10, 2007, at 22:54:22
> Every med affects everybody differently, but I would say the general consensus in here is that Parnate is stronger than Emsam.
>
> Perhaps you could increase your dose of Parnate like many other have? Or switch to Nardil? Or combine Parnate with a TCA (look up SLS old posts).
>
> Please keep us updated. Michael
Thanks for the response. Been functioning at 30mg parnate so could increase dosage but take as single dose or forget to take it later in the day. still get teary easy and sleep is poor - also pretty scattered. I think some problems are learned behavior from living one day at a time too long (25 years). Patch would keep dosage more constant and since not maxed on parnate might be able to compensate with larger emsam patch. Still uncertain about % impact on various neurotransmitters. Feel certain, from experience, that I need broad spectrum approach. also, closest I ever got to "normal" was use of zoloft and small dose of benzedrine. Pharmaceutical provider deterred doctor from continuing benzedrine and condition deteriorated on zoloft alone. since it seems selegiline degrades to form of amphetamine, I was hopeful it impacted dopamine in a manner beneficial to my condition. Prior to, an post, amphetamine, sleep has been minimal - sometimes every other night. While on benzedrine I slept normal 6-8 hours and woke refreshed. DO NOT WANT to be on meth or other dangerous type or level of amphetamine but feel the beneficial result may be attainable by a legitimate medication and hoping selegiline might be the answer. Any other comments???
Posted by Honore on March 11, 2007, at 11:26:31
In reply to Re: Parnate or Emsam Stronger? » UgottaHaveHope, posted by gargoyle on March 11, 2007, at 11:20:05
If you forget the later doses, Emsam might be a better method of absorption than oral doses.
You put the patch on and leave it on for 24 hours, and dont' have to remember later meds.
30 mg Parnate isn't really a very strong dose. Typical therapeutic range is 30-60 mg, but many people don't respond adequately to 30 mg, and often it can be given at higher doses than 60 mg (depending on pdoc).
So I would either go up on Parnate, or switch. Emsam affects those neurotransmitters. I don't think anyone knows exactly which ones are affected comparatively, but all Maois affect all Neurotransmitters that are broken down by Mao (an enzyme). It's different for different people in effectiveness, but I've found Emsam much more effective in both AD and energy, and sociability than Parnate ever was.
But if you would have trouble remember your later doses with Parnate, it might be a partial solution. But I wouldn't be satisfied with the response you're getting. What does you pdoc say?
Good luck with whichever you try.
Honore
Posted by UGottaHaveHope on March 11, 2007, at 11:41:48
In reply to selegiline patch, posted by gargoyle on March 10, 2007, at 15:51:48
Yes, I guess I would first look at increasing the Parnate dose.
And if you want to try to Emsam, now is a good time for you to do that. According to my pdoc, you can switch from Parnate or Nardil with no washout period, therefore take it tomorrow. And if it does not work out after a fair trial of 8-12 weeks, go back to Parnate with no washout.
Its your call. Prayers man, Michael
Posted by gargoyle on March 22, 2007, at 13:19:24
In reply to Re: selegiline patch » gargoyle, posted by UGottaHaveHope on March 11, 2007, at 11:41:48
Thanks for the input!!! See my doctor tomorrow and have gathered info from several sources. I seem to "plateau" at 30mg Parnate and although I've taken larger doses, have noticed no improvement so stay at the lower dose. Most info points toward combining a mood stabilizer or trying the emsam. Thanks again!! Perhaps I'll have some new info for you after tomorrow.
Posted by gargoyle on March 22, 2007, at 13:22:24
In reply to Re: Parnate or Emsam Stronger? » gargoyle, posted by Honore on March 11, 2007, at 11:26:31
Hi Honore! sent response meant to include you! Please see message to UGOTTAHAVEHOPE> thanks for your input.
This is the end of the thread.
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