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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 6 of 6. This is the beginning of the thread.
Posted by bipolarspectrum on June 27, 2005, at 17:47:44
Hi,
Lamictal sends me hypomanic when I take it for bipolar depression.. I'm wondering whether anyone has ever used topamax as a means to stop the lamictal-induced hypomania?? I read about this possible option on Dr. Ivan Goldberg's psycom site associated with Dr. Bob's site..
bps
Posted by SLS on June 27, 2005, at 18:44:25
In reply to Can TOPAMAX control LAMICTAL-induced mania?, posted by bipolarspectrum on June 27, 2005, at 17:47:44
> Hi,
> Lamictal sends me hypomanic when I take it for bipolar depression.. I'm wondering whether anyone has ever used topamax as a means to stop the lamictal-induced hypomania?? I read about this possible option on Dr. Ivan Goldberg's psycom site associated with Dr. Bob's site..
> bpsMy first reaction when I read this is to ask you if you would consider using Zyprexa or any other AP as an antimanic / stabilizer. I wish there were more anecdotes on the board describing the use of Abilify in such circumstances. It would be a nice alternative if weight gain is an issue. Regardless, you could take a short trial of Zyprexa just to see whether or not persuing this strategy is warranted.
- Scott
Posted by bipolarspectrum on June 27, 2005, at 19:37:37
In reply to Re: Can TOPAMAX control LAMICTAL-induced mania?, posted by SLS on June 27, 2005, at 18:44:25
Hey SLS,
I tried zyprexa with lamictal and I felt very anxious, like I had constant inner tension.. I'm wondering if topamax can be an anecdote for that?bps
Posted by SLS on June 27, 2005, at 20:30:49
In reply to Re: Can TOPAMAX control LAMICTAL-induced mania?, posted by bipolarspectrum on June 27, 2005, at 19:37:37
Hi BPS.
> I tried zyprexa with lamictal and I felt very anxious, like I had constant inner tension.
Darn.
> I'm wondering if topamax can be an anecdote for that?
I really don't know. The words you chose to describe your experience as "inner tension" are often used when akathisia is present. It would be an unusual reaction to Zyprexa. I doubt Topamax would help much if it is akathisia. You could perhaps use Seroquel instead of Zyprexa.
Have you tried Trileptal? I am taking it for bipolar depression and am experiencing intermittent improvements in combination with Lamictal. I can only pray that this stuff really sticks. I'm still not out of the woods yet.
Lamictal 150mg
Trileptal 900mg
Parnate 80mg
nortriptyline 100mg
Abilify 10mg
- Scott
Posted by bipolarspectrum on June 29, 2005, at 18:01:16
In reply to Re: Can TOPAMAX control LAMICTAL-induced mania? » bipolarspectrum, posted by SLS on June 27, 2005, at 20:30:49
Hey SLS,
I've tried trileptal but not at a dose above 600 mg.. Its definately an option.. How much of an antidepressant kick is trileptal having for u scott?
bps
Posted by SLS on June 29, 2005, at 19:21:10
In reply to Re: Can TOPAMAX control LAMICTAL-induced mania?, posted by bipolarspectrum on June 29, 2005, at 18:01:16
> Hey SLS,
> I've tried trileptal but not at a dose above 600 mg.. Its definately an option.. How much of an antidepressant kick is trileptal having for u scott?
> bps
Right now, it is not very potent at all. I have been taking 900mg for 11 days. When I first raised the dosage up from 600mg, the antidepressant effect was significant and developed within 36 hours. I had about 5 days when I was convinced that I was on my way towards remission. Unfortunately, the improvement plateaued and I have since lost ground. There is still a residual improvement, though, and I am hoping that further dosage increases will establish a more robust and stable response. I don't know how high my doctor will let me go, but I told him that I wanted to push the dosage. I look foward to going up to 1200mg. Right now, I am experiencing no side effects.All I can say is that Trileptal has produced a true antidepressant effect in conjunction with the other medications I am taking. The trick is getting it to stick.
- Scott
This is the end of the thread.
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