Psycho-Babble Medication Thread 412987

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Cubbybear-Willyee//Parnate Questions

Posted by bluebird on November 7, 2004, at 16:21:31

Hello there, I am taking 50mg of Parnate. I have been on this dose for 5 days now. I don't seem to be seeing or feeling many positive effects from it yet. I have been on it for a total of 7 weeks. I do feel aggitated on and off. Prior to this I was on Paxil I loved it at first and it worked very well. It kept my mind from running constantly. It was really the first relief I had ever had since about the age of 9 or 10 years old. I have Avoidant Personality Disorder, Social Phobia and really anything that has social in it causes severe panic and anziety, also depression. I thought the Parnate would be much more effective. Paxil pretty much got me into an over load because the dose had to continue being raised. I now have my memory back and am thinking pretty clearly now. Which on high levels of Paxil I was out of it, but felt no pain. It was out of control I can see that now. But doesn't Paxil work mainly on Seratonin? What all does Parnate work on? My head is much clearer but the anxiety and panic are back and not pleasant. Does it take Parnate a long time to work? I don't like my new PDoc. She is the only one I have found to prescribe MAOI's.
She is a very negative person. I am looking for someone new. Anyway, I didn't mean to stray from the subject. I have had tons of counceling along with the cognitive behavioral therapy along with more counceling, group therapy and it goes on. Both my Mother's & Father's sides of the family have all sorts of problems from agoraphobia to suicide to panic, anxiety you name it. I am the only one in my family to seek help. So, the family support isn't there. My husband is extremely supportive though. We live several states away from my family. You know everyday is like ground hog day. You get up and it all starts over again. It gets so tiring that it is frustrating. I just want so much for this Parnate to work. My next question is what are you both taking Parnate for? Also what else do you take with it, and Is there something that can be added to raise the Seratonin level in my case a little? My doctor has me quiet confused about it all. Oh, I also take clonazepam 1/2mg and hydroxizine I have been told I can take several, I usually take 2 at bedtime. I take a very high dose of the Clonazepam when I go out and it doesn't work as well on the Parnate as it did on the Paxil. It has taken the Paxil a very long time to leave my system it seems. Well, Your input would be appreciated and I appoligize for this being so long. Thanks, bluebird

 

Re: Cubbybear-Willyee//Parnate Questions

Posted by Willyee on November 8, 2004, at 15:03:37

In reply to Cubbybear-Willyee//Parnate Questions, posted by bluebird on November 7, 2004, at 16:21:31

> Hello there, I am taking 50mg of Parnate. I have been on this dose for 5 days now. I don't seem to be seeing or feeling many positive effects from it yet. I have been on it for a total of 7 weeks. I do feel aggitated on and off. Prior to this I was on Paxil I loved it at first and it worked very well. It kept my mind from running constantly. It was really the first relief I had ever had since about the age of 9 or 10 years old. I have Avoidant Personality Disorder, Social Phobia and really anything that has social in it causes severe panic and anziety, also depression. I thought the Parnate would be much more effective. Paxil pretty much got me into an over load because the dose had to continue being raised. I now have my memory back and am thinking pretty clearly now. Which on high levels of Paxil I was out of it, but felt no pain. It was out of control I can see that now. But doesn't Paxil work mainly on Seratonin? What all does Parnate work on? My head is much clearer but the anxiety and panic are back and not pleasant. Does it take Parnate a long time to work? I don't like my new PDoc. She is the only one I have found to prescribe MAOI's.
> She is a very negative person. I am looking for someone new. Anyway, I didn't mean to stray from the subject. I have had tons of counceling along with the cognitive behavioral therapy along with more counceling, group therapy and it goes on. Both my Mother's & Father's sides of the family have all sorts of problems from agoraphobia to suicide to panic, anxiety you name it. I am the only one in my family to seek help. So, the family support isn't there. My husband is extremely supportive though. We live several states away from my family. You know everyday is like ground hog day. You get up and it all starts over again. It gets so tiring that it is frustrating. I just want so much for this Parnate to work. My next question is what are you both taking Parnate for? Also what else do you take with it, and Is there something that can be added to raise the Seratonin level in my case a little? My doctor has me quiet confused about it all. Oh, I also take clonazepam 1/2mg and hydroxizine I have been told I can take several, I usually take 2 at bedtime. I take a very high dose of the Clonazepam when I go out and it doesn't work as well on the Parnate as it did on the Paxil. It has taken the Paxil a very long time to leave my system it seems. Well, Your input would be appreciated and I appoligize for this being so long. Thanks, bluebird


Hi there,this is just typical proof how everyone is different.I work on a sales floor so you can imagine how difficult it is for me to handle anxiety,i am able to totaly control it at work,but at times when i do it turns into hyperness.Also doing so when i get home im exhausted,fighting anxiety seems to wear and tear the body as well.

As in your case,all i can say is like you i take klonopin as needed,....25-.5 a day,but i will tell you for whatever reason klonopin does something to the parnate and creates a horrable feeling,so i try not to take it,and if i do i take klonopin ALONE,not in conjunction with my parnate dose.Klonopin for me is more effective take spaced apart from parnate,too bad sounds like a simple answer,a antidepressant that works,and a anti-anxiety that works,just take togther,but it doesent pan out that way.

I find actualy taking a small pieace of vivarin smoothes out anxiety more with parnate than a sedative,the parnate sedative combo seems to heighten anxiety and depression.

Lastly,one thing you might look into is trying a beta blocker to parnate over a benzo,ask ya doc about the possability,also from what i read nardil might serve as a better option for you is your anxiety seems to be worsening.I guess i should apologize to,this post wasnt exactly short either.

 

Re: Cubbybear-Willyee//Parnate Questions » bluebird

Posted by cubbybear on November 9, 2004, at 9:51:14

In reply to Cubbybear-Willyee//Parnate Questions, posted by bluebird on November 7, 2004, at 16:21:31

> Hello there, I am taking 50mg of Parnate. I have been on this dose for 5 days now. I don't seem to be seeing or feeling many positive effects from it yet. I have been on it for a total of 7 weeks.

I'm concerned since, if you have been on a dose of, say 40 mg. for at least 6 weeks, you probably should have felt some relief from the DEPRESSION by now. I'd give the 50 mg. another couple of weeks, then discuss the situation again with your doctor. Some people need much higher-than-the recommended doses.

I do feel aggitated on and off. Prior to this I was on Paxil I loved it at first and it worked very well. It kept my mind from running constantly. It was really the first relief I had ever had since about the age of 9 or 10 years old. I have Avoidant Personality Disorder, Social Phobia and really anything that has social in it causes severe panic and anziety, also depression. I thought the Parnate would be much more effective.

If your main problem is anxiety, then I wonder about the use of an MAOI, or any anti-depressant for that matter. But I'm not a doctor. . .it's hard for me to make a judgement about your symptoms, and the relative "amounts" of anxiety and depression.

But doesn't Paxil work mainly on Seratonin? What all does Parnate work on?

Parnate indirectly serves to increase the levels of serotonin, norepinephrine, and dopamine in storage sites in the brain and throughout the central nervous system.

Does it take Parnate a long time to work?

Like other ADs, the therapeutic effects of Parnate are normally not reached until a minimum of 3-4 weeks.

. My next question is what are you both taking Parnate for?

At present, I'm taking only Parnate and it is on a continuous basis to keep major depression in remission, and the high anxiety I get as a symptom of it.

Also what else do you take with it, and Is there something that can be added to raise the Seratonin level in my case a little?

I'm not sure about augmentation strategies.

My doctor has me quiet confused about it all.

That's what the Internet is for! There's an endless amount of material out there for you to learn even more than most doctors know.

Oh, I also take clonazepam 1/2mg and hydroxizine I have been told I can take several, I usually take 2 at bedtime. I take a very high dose of the Clonazepam when I go out and it doesn't work as well on the Parnate as it did on the Paxil.

I was taking Clonazepam before bed to help me sleep and I found that, contrary to Willyee's experience, it was a perfect compliment to Parnate. I never had any problem taking it or Xanax to relieve anxiety, whether I was on Parnate or not. As you can see, everybody reacts differently.
I think you should give the50 mg. Parnate dose a little more time, and either way, discuss with the doctor what you can do to alleviate your anxiety--another medication that would be safe to take with Parnate. I can tell you that NEURONTIN is safe with Parnate and it might be the answer. Good luck


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