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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 19 of 19. This is the beginning of the thread.
Posted by Dinah on July 15, 2003, at 22:23:35
In reply to Topamax -- appetite loss or metabolism gain?, posted by kashley on July 15, 2003, at 19:03:52
Originally posted by kashley 7/15/03
> Hi all,
>
> I'm a newbie to this board and saw the loads of threads about the weight loss experienced by those of you on Topamax. Here's my deal:
>
> I have clinical depression and occasionally lean into the bipolar arena. I've been LOVING life on Effexor XR for the past 15 months (at 300 mg. for about six months now), but like several people in the posts I read, I gained 38 pounds in a mighty short period of time. My doctor said it had nothing to do with Effexor XR and he left it at that.
>
> My doctor died about five weeks ago. (How many of you can say THAT?)
>
> Anyway, today I saw a new doctor and she was immediately concerned about the weight gain and said it WAS probably because of the Effexor XR! Knowing that I would NOT give up my Effexor XR for anything, she gave me a scrip for Topamax. She wants me to start at 25 mg per day and work my way up to 200 mgs gradually (she gave me a schedule to follow).
>
> As much as I would love to think Topamax will help me lose some of the weight I gained from Effexor, the fact of the matter is ... I don't eat a lot! At all! Ever! (Well, okay, maybe the occasional chocolate pig-out when I'm P.M.S.ing).
>
> Really, my daily caloric intake is rarely over 1000 per day -- simply because I'm never hungry and drinking water (which I love) fills me up. For exercise, I rollerblade a few hours each week and do some upper body work as well (not much, mind you).
>
> So, here I am, barely eating as it is, yet gained an obscene amount of weight in a ridiculously short period of time, probably because of my beloved Effexor XR. My daily food intake (generally healthy foods) is obviously not the reason for not being able to lose any of this weight or for having gained it in the first place.
>
> So ... is Topamax going to make me eat even less???? Or can any of you who have lost weight while taking Topamax truly say that your loss was not as a direct result of decreased appetite?
>
> Help!
>
Posted by Dinah on July 15, 2003, at 22:26:01
In reply to Re: Topamax -- appetite loss or metabolism gain?, posted by Dinah on July 15, 2003, at 22:23:35
Posted by galkeepinon on July 15, 2003, at 23:11:31
In reply to Re: Topamax -- appetite loss or metabolism gain?, posted by Dinah on July 15, 2003, at 22:23:35
hi kashley,
wow-I am really wondering what caused you to gain that weight in the first place!!?? I'm on Effexor also as well as Topamax. I've lost 25 Lbs on the Topamax in 2 months.
**For me, the Topamax definately has made me eat less!!! Most definately!!! I do belive that my weight loss WAS a direct result of my decreased appetite when I started Topamax but I also noticed something else.......when I increased my dosage to 200mg a day-the weight started coming off faster and faster. I think there is a metabolic component that Topamax is involved with.
Let me know if you have anymore questions.
I love the med-I gained weight on previous psych meds and the Topamax has helped me to lose some of it while also helping my moods.Gal
> > Hi all,
> >
> > I'm a newbie to this board and saw the loads of threads about the weight loss experienced by those of you on Topamax. Here's my deal:
> >
> > I have clinical depression and occasionally lean into the bipolar arena. I've been LOVING life on Effexor XR for the past 15 months (at 300 mg. for about six months now), but like several people in the posts I read, I gained 38 pounds in a mighty short period of time. My doctor said it had nothing to do with Effexor XR and he left it at that.
> >
> > My doctor died about five weeks ago. (How many of you can say THAT?)
> >
> > Anyway, today I saw a new doctor and she was immediately concerned about the weight gain and said it WAS probably because of the Effexor XR! Knowing that I would NOT give up my Effexor XR for anything, she gave me a scrip for Topamax. She wants me to start at 25 mg per day and work my way up to 200 mgs gradually (she gave me a schedule to follow).
> >
> > As much as I would love to think Topamax will help me lose some of the weight I gained from Effexor, the fact of the matter is ... I don't eat a lot! At all! Ever! (Well, okay, maybe the occasional chocolate pig-out when I'm P.M.S.ing).
> >
> > Really, my daily caloric intake is rarely over 1000 per day -- simply because I'm never hungry and drinking water (which I love) fills me up. For exercise, I rollerblade a few hours each week and do some upper body work as well (not much, mind you).
> >
> > So, here I am, barely eating as it is, yet gained an obscene amount of weight in a ridiculously short period of time, probably because of my beloved Effexor XR. My daily food intake (generally healthy foods) is obviously not the reason for not being able to lose any of this weight or for having gained it in the first place.
> >
> > So ... is Topamax going to make me eat even less???? Or can any of you who have lost weight while taking Topamax truly say that your loss was not as a direct result of decreased appetite?
> >
> > Help!
> >
>
>
Posted by kashley on July 16, 2003, at 10:27:21
In reply to Re: For kashley Re: Topamax........................ » galkeepinon, posted by kashley on July 16, 2003, at 8:09:25
Hi Gal,
First, thank you Dinah for redirecting my message to the right board! This is a confusing place!
Gal, what's your psyche diagnosis? So, you're on Effexor (great stuff, ain't it?), but then your doctor added the Topomax because .... ? To lose some of the weight that you had gained on previous meds?
And here's a general question to all of you on Topomax -- what time of day do you take it? I decided to start off taking it in the evening when I get home from work. Since fatigue could be a side effect, I don't want to be falling asleep on the job! But, I'm a bit worried about the evening dosage.
See, ever since I started taking Effexor last year, I sleep really well and have the BEST dreams (I rarely used to dream, rarely had nice ones and rarely remembered them during my waking hours). On Effexor, I dream EVERY night, the dreams are pleasant, almost always feature people that I know and like, many are in color and I remember them after I wake up. That's a really neat thing, ya know? And I don't want evening doses of Topamax to screw that up.
Okay, back to the weight thing. I'm curious -- those of you who have lost weight on Topamax (for whatever reasons) will you all gain the weight back if you taper down your dosage or go off of it? Is it really nothing more than a prescription diet pill with mood-enhancing effects???
So many questions!!! Only ten fingers to type with!!!
Posted by galkeepinon on July 16, 2003, at 16:47:32
In reply to Re: Topamax -- appetite loss or metabolism gain???, posted by kashley on July 16, 2003, at 10:27:21
Hi kashley, I'm bipolar. Effexor works well for me. My doctor added Topamax yep-not only to aid in weight loss from the weight I gained from all the other psych meds over the years but as an add-on to balance out my moods. He wanted to see if not being on any antidepressants would work for me-it was something I had never tried before. Unfortunately a low dose of Effexor with the Topamax works just fine.
As far as the time of day I take my Topamax....I have had to experiment. Currently, I am taking 100mg at 3pm and 100mg at 10pm, it seems to be working. I can't take Effexor any later than 7am or I'm up at night!> Hi Gal,
>
> First, thank you Dinah for redirecting my message to the right board! This is a confusing place!
>
> Gal, what's your psyche diagnosis? So, you're on Effexor (great stuff, ain't it?), but then your doctor added the Topomax because .... ? To lose some of the weight that you had gained on previous meds?
>
> And here's a general question to all of you on Topomax -- what time of day do you take it? I decided to start off taking it in the evening when I get home from work. Since fatigue could be a side effect, I don't want to be falling asleep on the job! But, I'm a bit worried about the evening dosage.
>
> See, ever since I started taking Effexor last year, I sleep really well and have the BEST dreams (I rarely used to dream, rarely had nice ones and rarely remembered them during my waking hours). On Effexor, I dream EVERY night, the dreams are pleasant, almost always feature people that I know and like, many are in color and I remember them after I wake up. That's a really neat thing, ya know? And I don't want evening doses of Topamax to screw that up.
>
> Okay, back to the weight thing. I'm curious -- those of you who have lost weight on Topamax (for whatever reasons) will you all gain the weight back if you taper down your dosage or go off of it? Is it really nothing more than a prescription diet pill with mood-enhancing effects???
>
> So many questions!!! Only ten fingers to type with!!!
>
Posted by galkeepinon on July 16, 2003, at 16:51:10
In reply to Re: Topamax -- appetite loss or metabolism gain??? » kashley, posted by galkeepinon on July 16, 2003, at 16:47:32
Do you really think that the 38 pounds you gained was caused by the Effexor? I know you said 1 doc said no but your new one said yes. What do YOU think? I wonder myself, because I'm on it.
Posted by kashley on July 16, 2003, at 17:31:11
In reply to kashley--------BTW....................., posted by galkeepinon on July 16, 2003, at 16:51:10
As much as I'd love to blame the weight gain on the fact that I have entered my late 30's, I just can't. Considering that my nickname had been "Barbie" for over 15 years (because of my Barbie doll-like proportions), I simply can't blame a 38-pound weight gain in a six-month period of time on the "aging process", ya know?
My eating habits have been the same since I began living on my own at age 17. The only change in my life was the addition of Effexor to it. And I swear to goodness -- one day my clothes fit just fine, the next day I was buying a new wardrobe because NOTHING fit. Do you have any idea how ... WEIRD... it is to outgrow your panties and bras at my age?? I hate to get this graphic but, do you know how uncomfortable a tight g-string can be?
I went from a size 0-1 to a size 9-10. I think the reason why my initial male doctor didn't think the weight gain was an issue was because he was seriously obese (he had a heart attack and died at age 42 because of his weight) and I just don't think 38 pounds in either direction (gain or loss) would have startled him.
What are your thoughts?
Posted by kashley on July 18, 2003, at 16:01:01
Hi, its Kashley again. The thread I started about hoping to lose weight on Topamax after gaining on Effexor got buried. This is such an active board!
Here's what I posted in response to your question to me about my 38 lb. weight gain.
As much as I'd love to blame the weight gain on the fact that I have entered my late 30's, I just can't. Considering that my nickname had been "Barbie" for over 15 years (because of my Barbie doll-like proportions), I simply can't blame a 38-pound weight gain in a six-month period of time on the "aging process", ya know?
My eating habits have been the same since I began living on my own at age 17. The only change in my life was the addition of Effexor to it. And I swear to goodness -- one day my clothes fit just fine, the next day I was buying a new wardrobe because NOTHING fit. Do you have any idea how ... WEIRD... it is to outgrow your panties and bras at my age?? I hate to get this graphic but, do you know how uncomfortable a tight g-string can be?
I went from a size 0-1 to a size 9-10. I think the reason why my initial male doctor didn't think the weight gain was an issue was because he was seriously obese (he had a heart attack and died at age 42 because of his weight) and I just don't think 38 pounds in either direction (gain or loss) would have startled him.
What are your thoughts?
Posted by galkeepinon on July 19, 2003, at 14:16:58
In reply to Galkeepinon -- re Effexor gain, posted by kashley on July 18, 2003, at 16:01:01
Hey there, yeah, threads get lost around here a lot it seems. Anyway, here's my thoughts. True, a 38-pound weight gain in a six-month period of time is quite a bit. I actually gained close to that in 1 month's time when I went on Depakote for a short amount a time EEK!!!!! I have heard in the past and read in the drug literature on Effexor that anorexia or weight loss can be a side effect. For me, it wasn't. In the beginning (like the first 2 weeks) I lost about 6 Lbs.-but it came back. I truly don't believe Effexor has the added benefit of weight loss. I can't even say that any anti-depressants MADE me lose weight. BUT, I can say that the only anti-depressant I DIDN'T gain weight on was Celexa. I hope this helps. If you need anything else please let me know :)
I wish you the best.
**Doctors still cease to amaze me..... I've had about 5 of them since I began this journey with my mental health problems and each one of them have acted differently on the weight gain issue with meds.
Some simply ignore a patient's concerns, Some are very caring and cooperative, and some simply do not know, after all, they are human. It is hard to answer a patient when they ask their doctor "Will this drug or that drug make me gain weight" when the primary, most important issue at hand is that of what any doctor would expect it to be-"Will this drug or that drug make me feel better and/or help me to cope better/help therapy be more productive......whatever?"
Sometimes I feel really bad for doctors-they have a tough job, and sometimes I get angry with the ones that do not listen. If they listen, and truly cannot help then they need to explain to their patients, but we all have egos and doctors do too and sometimes they let theirs get in the way. But when they truly do not listen and instead totally ignore not only concerns of this weight issue that so very many patients experience, but also don't set some sort of example (and I don't necessarily mean a physical one here) it is sad.That is why I am always doing my research. I look up every medication I am on. I try it out. I ask my docs a lot of questions. I have been called annoying. I don't care. I have been "fired" I don't care. I used to. I would cry about it. I don't anymore. And you know where all that got me? It led me to a wonderful, understanding, intelligent, patient, kind, extremely helpful primary care physician and a well-known, reputable, good-listener, open-minded, flexible, kind psychiatrist.
To me, it was well-worth it!Keep me posted on your progress!
Gal
> Hi, its Kashley again. The thread I started about hoping to lose weight on Topamax after gaining on Effexor got buried. This is such an active board!
>
> Here's what I posted in response to your question to me about my 38 lb. weight gain.
>
> As much as I'd love to blame the weight gain on the fact that I have entered my late 30's, I just can't. Considering that my nickname had been "Barbie" for over 15 years (because of my Barbie doll-like proportions), I simply can't blame a 38-pound weight gain in a six-month period of time on the "aging process", ya know?
>
> My eating habits have been the same since I began living on my own at age 17. The only change in my life was the addition of Effexor to it. And I swear to goodness -- one day my clothes fit just fine, the next day I was buying a new wardrobe because NOTHING fit. Do you have any idea how ... WEIRD... it is to outgrow your panties and bras at my age?? I hate to get this graphic but, do you know how uncomfortable a tight g-string can be?
>
> I went from a size 0-1 to a size 9-10. I think the reason why my initial male doctor didn't think the weight gain was an issue was because he was seriously obese (he had a heart attack and died at age 42 because of his weight) and I just don't think 38 pounds in either direction (gain or loss) would have startled him.
>
> What are your thoughts?
>
>
Posted by kashley on July 19, 2003, at 15:20:04
In reply to Re: Galkeepinon -- re Effexor gain » kashley, posted by galkeepinon on July 19, 2003, at 14:16:58
Hi Gal,
Well, don't know how, don't know why, but -- here I am on day five with Topamax and I've lost 2 pounds. Now, that may not sound like any big deal (considering that you can GAIN more than that just being constipated!), but my period is due tomorrow and my weight should be A LOT higher than it is today because I usually swell up like water balloon. So, who knows?
You mentioned some of the many listed side effects of Effexor as being anorexia (decreased appetite) and weight loss. Well, oddly enough, I had an interesting conversation with my mother the other day. My mom has schizo effective disorder and a bit of OCD, has been hospitalized more times than I can count and has been on more meds than I care to recall.
Without conversing with me, my mom's latest doctor during her most recent hospitalization switched her main med to Effexor. She's also taking Lithium and Buspar (did I spell that right?). Anyway, she's been on it for about 8 or 9 months now and the Effexor seems to be working really well for her. She usually decompensates every six months like clockwork, so going for 8 or 9 months is REALLY terrific.
I had a subsequent conversation with her doctor and he told me that if a certain med works well for one family member it (generally) will work well on other family members.
Anyway, the interesting conversation with my mom ... she had a follow up with her doc last week and he asked her (of course) how she was doing and ... had she GAINED any weight from the Effexor!
Now, my mom is 78 years old and her vanity went out the window years ago along with her scale, so she doesn't blink if she goes up or down a clothing size -- plus all of her clothing has lots of elastic or is very free flowing, rather than form fitting. BUT, she did tell me (and her doctor) that she has formed one hell of a spare tire around her waist since she started the Effexor! Granted, my weight gain was overall but I did gain 7 inches in my waist line, compared to only 3 in my hips.
I thought that was interesting!
Kashley
Posted by Kacy on July 20, 2003, at 10:56:21
In reply to Re: Galkeepinon -- re Effexor gain, posted by kashley on July 19, 2003, at 15:20:04
My weight on Effexor is centered on the waist, although it is elsewhere, too. I never had clothes be too tight at the waist before. That's because I couldn't even get into clothes that would be tight at the waist if I gained any weight because the proportional hip gain was always there keeping me out of that size.
I can't lose weight on Effexor. I was a successful dieter before. I have gained weight every now and then, but, sooner or later, I slowly took it off with moderate dieting and then kept it off with ease. I unfortunately had twenty pounds on when I went on Effexor. That's the most I was ever overweight before. Six months later I increased to thirty pounds. I beat most of the last ten lbs (until recently) but can't take off the twenty.
Recently I have been battling a new gain. Has anyone ever gained weight from beginning vitamins? I swear, that is the only real difference since I gained eight more pounds. I just quit vitamins because they are hard to take, and five of the eight pounds are gone. How can this be? I'm afraid to take the vitamins again. I never took them before and really wanted to try taking them. Anyone familiar with this? I took in an extra couple of glasses of water a day with them; I am not a water drinker and don't drink a lot of liquids. That's not a lot of water, is it? I have tried to drink more water before and I never put on weight doing that. I added at least that much water a day for comparable periods of time. I need the two glasses to choke down those vitamins and minerals because I don't swallow pills well. I took the vitamins a lot more consistently than the minerals, which are in four pills instead of one. Has anyone experienced this?
Posted by LynnPerley on July 22, 2003, at 22:57:50
In reply to Re: Galkeepinon -- re Effexor gain, posted by Kacy on July 20, 2003, at 10:56:21
I think I have gained on Effexor due to the constant but minimal stomach irritation it causes - after the inital nausea side effect goes away - I feel as if I always need something in my stomach, and if I go too long without eating something I get physically ill.
I'm going to try and lose the 20+ pounds I have gained on effexor - I've done it before effexor (lifetime WW member) so I'll let you all know.
Posted by kashley on July 23, 2003, at 8:27:46
In reply to Re: Galkeepinon -- re Effexor gain » Kacy, posted by LynnPerley on July 22, 2003, at 22:57:50
I didn't have any lasting side effects (besides the weight gain) on Effexor. I had a few initial ones -- couldn't sleep, had sudden severe hot flashes and nausea (at night) but all of that went away within the first two weeks.
I've always been a dieting pro and BELIEVE ME, I tried everything to lose the 38 pounds I gained on Effexor and I couldn't lose an OUNCE. I ate rabbit food (salads, etc.) like crazy, did cardio workouts until my legs turned to rubber, took Trim Spa for a while -- nothing! NOTHING!
I'm now on day 10 of Topamax and I've lost 4 pounds. I'm not getting my hopes up yet, but I will keep you guys informed.
Posted by Brittany on July 24, 2003, at 19:59:25
In reply to Re: Topamax -- appetite loss or metabolism gain?, posted by Dinah on July 15, 2003, at 22:23:35
> Originally posted by kashley 7/15/03
>
> > Hi all,
> >
> > I'm a newbie to this board and saw the loads of threads about the weight loss experienced by those of you on Topamax. Here's my deal:
> >
> > I have clinical depression and occasionally lean into the bipolar arena. I've been LOVING life on Effexor XR for the past 15 months (at 300 mg. for about six months now), but like several people in the posts I read, I gained 38 pounds in a mighty short period of time. My doctor said it had nothing to do with Effexor XR and he left it at that.
> >
> > My doctor died about five weeks ago. (How many of you can say THAT?)
> >
> > Anyway, today I saw a new doctor and she was immediately concerned about the weight gain and said it WAS probably because of the Effexor XR! Knowing that I would NOT give up my Effexor XR for anything, she gave me a scrip for Topamax. She wants me to start at 25 mg per day and work my way up to 200 mgs gradually (she gave me a schedule to follow).
> >
> > As much as I would love to think Topamax will help me lose some of the weight I gained from Effexor, the fact of the matter is ... I don't eat a lot! At all! Ever! (Well, okay, maybe the occasional chocolate pig-out when I'm P.M.S.ing).
> >
> > Really, my daily caloric intake is rarely over 1000 per day -- simply because I'm never hungry and drinking water (which I love) fills me up. For exercise, I rollerblade a few hours each week and do some upper body work as well (not much, mind you).
> >
> > So, here I am, barely eating as it is, yet gained an obscene amount of weight in a ridiculously short period of time, probably because of my beloved Effexor XR. My daily food intake (generally healthy foods) is obviously not the reason for not being able to lose any of this weight or for having gained it in the first place.
> >
> > So ... is Topamax going to make me eat even less???? Or can any of you who have lost weight while taking Topamax truly say that your loss was not as a direct result of decreased appetite?
> >
> > Help!
> >
>
>I can completely understand your frustration/love of effexor. I have been on effexor for 5 years and on neurontin for 4 years. Neurontin and Topomax are similar and I have had thoughts of changing to Topomax. The fact that it has the potential for weight loss is a major factor for me. In the last 5 yeras I have gained 70 lbs. and I really think it is effexor. I have always been able to exercise and get the weight off if I gained a few lbs. but since the effexor....the scale keeps increasing and I am at the point where my physical appearance is a larger depression. I just increased my effexor from 150 ro 225mg to help with the depression that the effexor is partially causing (the weight gain). I would be interested to hear of any research or experiences that would help me make that decision. I am not excited about putting my body through a medication change - but I will if I need to. Also, will Topomax take care of the depression and the anxiety blips from which I suffer?
Posted by kashley on July 25, 2003, at 16:32:48
In reply to Re: Topamax -- appetite loss or metabolism gain? » Dinah, posted by Brittany on July 24, 2003, at 19:59:25
My initial post has gone in some interesting directions, but I still hope to get a response to my initial question / concern about Topamax.
Is the weight loss that Topamax seems to bring about caused only by decreased appetite or something else? I normally live a healthy low-calorie lifestyle -- if Topamax makes me eat even LESS, it will very unhealthy.
Does Topamax effect the way your body digests the food that you eat. Does it effect your metabolism?
Kashley
Posted by LynnPerley on July 25, 2003, at 19:59:08
In reply to Re: Topamax -- appetite loss or metabolism gain?, posted by kashley on July 25, 2003, at 16:32:48
I'm not familiar with Topomax so I can't answer your question, but if I could possibly offer an observation - are you sure your problem is not that you don't eat enough? It seems like you may eat very little compared to your activity level, and eating too little may put your body into starvation mode and make it hard to lose any weight at all. Your metabolism may be messed up from your eating habits. If this offends, I'm sorry.
Posted by kashley on July 25, 2003, at 23:01:13
In reply to Re: Topamax -- appetite loss or metabolism gain? » kashley, posted by LynnPerley on July 25, 2003, at 19:59:08
Hi Lynn,
That's a fair enough question. My eating habits have been the same, as well as my activity level, for as long as I can remember. My weight had stayed the same for as long as I could remember as well. I added Effexor to my life in January of 2002 and by June of 2002, I gained 38 pounds. 38 pounds in six months.
And that's where my weight stayed for 13 months, now in July of 2003.
Kashley
Posted by Stan on July 26, 2003, at 1:05:52
In reply to Re: Topamax -- appetite loss or metabolism gain?, posted by kashley on July 25, 2003, at 16:32:48
> My initial post has gone in some interesting directions, but I still hope to get a response to my initial question / concern about Topamax.
>
> Is the weight loss that Topamax seems to bring about caused only by decreased appetite or something else? I normally live a healthy low-calorie lifestyle -- if Topamax makes me eat even LESS, it will very unhealthy.
>
> Does Topamax effect the way your body digests the food that you eat. Does it effect your metabolism?
>
> Kashley___________
kashley: someone posted a link the other day which led to some info about a similar drug, zonegran. if you follow this link (below) and then scroll down, you'll see some studies to click on that indicate that zonegran helps promote weight loss by some mechanism other than simply reducing the patients' appetite and causing them to restrict food intake. i just glanced at a couple of the articles -- i don't know if it raises the metabolic rate or operates in some other way to cause this effect (researchers may not even fully understand this). topamax should perform in a similar fashion as zonegran for weight loss -- not all mood-stabilizing anti-epilepsy drugs have this side effect, but these two seem to. here's the link:
Posted by kashley on July 26, 2003, at 8:25:16
In reply to Re: Topamax -- appetite loss or metabolism gain? » kashley, posted by Stan on July 26, 2003, at 1:05:52
Stan,
Thanks for the link. But I really, really would like to know specifically about Topamax and the personal experiences by the folks here on the babble board. I can read clinical studies all day until my eyes pop out, but they don't mean much to me.
Perfect example -- clinical studies say that side effects of effexor include decreased appetite and anorexia, yet many of us here on the board (like me) actually experieced ridiculous weight GAIN on effexor which is NOT listed as a side effect of Effexor in clinical studies.
Kashley
This is the end of the thread.
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