Psycho-Babble Medication Thread 49693

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Norephramine is it addictive ?

Posted by felix on November 30, 2000, at 14:46:19

Would anyone out there care to comment if there is a Norephramine syndrome and thats why Effexor has so much withdrawal contraversial post ?
It has such a quick brain clearing strong brightness that I'm still recovering from the idea, that a drug is legal does this. Plus I only had it a week and half and when I missed a day I could'nt get of the floor for 24 hours. I felt like I was glued to it.

I'm new to drugs like Prozac and Effexor.
The prozac has stability written on it I feel, but the Effexor I'm not sure of. I have little trust of anything that good which feels like an illegal brew. I read about the clinical trial process, and they don't have proper trials for withdrawal or long term repurcussions. Also Effexor works on crack cocaine withdrawal. So this whole Norephramine/Effexor issue has me a bit scared. Do cocaine addicts need Norephramine ? If so the only drugs that help that problem have real addiction issues. And Low and behold so does Effexor.

From where I stand drug research is pressurised by need. It costs Billions just to get FDA for a basic need drug like depression trialed for human toxicity.

I have read abstracts from the Effexor trials and all the talk is on Neurotransmitter action and postive Vs Placebo. Anything on addiction gets written in later as an afternote. I realize Effexor does not have dosage dependancy and bypasses the CNS feedback loop.

Can this be true. Can a drug this strong be safe ? Replies in Neurologileze only.

Re: Norephramine is it addictive ?

Posted by stjames on November 30, 2000, at 20:36:18

In reply to Norephramine is it addictive ?, posted by felix on November 30, 2000, at 14:46:19

Cocaine addicts have depleted lots of NT's, including
nor-e. Any AD can help with this. Just because a psyco med is effective in treating illicits abuse
does not render these meds suspect. The withdrawal syndrome
from Effexor has to do with it's short action (and being a stong
med) I am assuming you mean norepinephrine by Norephramine. NT's and
other essencial things are not addictive.

To be addictive you need 1) an intital rush (whatever you want to call it)
2) Tolerance and 3) withdrawal when agent is stopped. In Effexor any positive effects
take weeks to develop and tolerance does not happen. If you call poop out tolerance
the time scale that this happens is off by a magnitude, years instead of weeks or months.

I've started and stopped Effexor countless times since 1994 without
significant event. Any problems are limited to at most a week. It is a strong med that leave the body
quickly. It is reasonable to assume this will cause problems.

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