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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 6 of 6. This is the beginning of the thread.
Posted by Bill on January 9, 2000, at 12:53:47
Hello, I have treatment resistant depression and have been on many meds including high dose Effexor XR. I have decided to go on an MAOI. But I cant make my mind up which one to go on. My specific question is:
"Which MAOI has the least anti-chloringeric(sp?) side effects?"
I was on a TCA and did not like the anti-chloringergic side effects. I want to try to avoid this on the MAOI.
Also, I have done best on stimulating antidepresssants so far. Wellbutrin and high dosage Effexor XR I have done best on. Are all the MAOIs stimulating? I know Parnate is the most stimulating but are all of them pretty stimulating?
Thanks
Posted by anita on January 9, 2000, at 19:48:22
In reply to Important MAOI question, posted by Bill on January 9, 2000, at 12:53:47
Hi,
I think Parnate and Seligiline have less anticholinergic side effects than Nardil or Marplan. Which side effects in particular do you want to avoid?
Parnate is generally stimulating, while Nardil is generally relaxing.anita
> Hello, I have treatment resistant depression and have been on many meds including high dose Effexor XR. I have decided to go on an MAOI. But I cant make my mind up which one to go on. My specific question is:
>
> "Which MAOI has the least anti-chloringeric(sp?) side effects?"
>
> I was on a TCA and did not like the anti-chloringergic side effects. I want to try to avoid this on the MAOI.
>
> Also, I have done best on stimulating antidepresssants so far. Wellbutrin and high dosage Effexor XR I have done best on. Are all the MAOIs stimulating? I know Parnate is the most stimulating but are all of them pretty stimulating?
>
> Thanks
Posted by Bill on January 9, 2000, at 23:51:20
In reply to Re: Important MAOI question, posted by anita on January 9, 2000, at 19:48:22
> Hi,
>
> I think Parnate and Seligiline have less anticholinergic side effects than Nardil or Marplan. Which side effects in particular do you want to avoid?I want to avoid "mental fog" type side effects. I had that on TCAs and could not stand it. Felt like I was in a haze all the time on TCAs.
Posted by S. Suggs on January 10, 2000, at 5:58:05
In reply to Re: Important MAOI question, posted by Bill on January 9, 2000, at 23:51:20
Bill: Im on 60 mg parnate. Have been for about 6-8 weeks with the best results. I too have had problems like you with TCA's. Parnate certainly clears my head (I,m ADD-H with Dysthymia). Also, I take lithium 900 mg daily. The results have been very good. Best wishes and blessings with your choice.
S. Suggs
Posted by Bill on January 10, 2000, at 6:27:06
In reply to Re: Important MAOI question, posted by Bill on January 9, 2000, at 23:51:20
Also I want to find out which class the MAOIs fall into. I read on another website that there are two classes of MAOIs. MAO type A and MAOI type B. Where does Parnate, Nardil and Marplan fall in this category thing?
Thanks
Posted by Elizabeth on January 10, 2000, at 8:05:43
In reply to Re: Important MAOI question, posted by Bill on January 10, 2000, at 6:27:06
> Also I want to find out which class the MAOIs fall into. I read on another website that there are two classes of MAOIs. MAO type A and MAOI type B. Where does Parnate, Nardil and Marplan fall in this category thing?
They inhibit both types of MAO.
At low doses, selegiline preferentially inhibits type B, while clorgyline and moclobemide preferentially inhibit type A.
This is the end of the thread.
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