Psycho-Babble Medication Thread 15056

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Anyone tried pramipexole (Mirapex)?

Posted by anita on November 12, 1999, at 0:58:11

Just wondering if anyone's tried this for depression (atypical), and what dose was used.

thanks,
anita

 

Re: Anyone tried pramipexole (Mirapex)?

Posted by Bruce on November 12, 1999, at 10:30:13

In reply to Anyone tried pramipexole (Mirapex)?, posted by anita on November 12, 1999, at 0:58:11

> Just wondering if anyone's tried this for depression (atypical), and what dose was used.
>
> thanks,
> anita


I too am wondering this. I have tried in vain to locate an overseas supplier. AndewB posts on this board, and likes the drug amisulpride which in low doses has a similar effect as Mirapex (stimulates D2/D3 receptors). Works wonders on his anhedonia. I believe Mirapex would work too.

Bruce

 

Re: Anyone tried pramipexole (Mirapex)?

Posted by MA on November 12, 1999, at 11:04:07

In reply to Re: Anyone tried pramipexole (Mirapex)?, posted by Bruce on November 12, 1999, at 10:30:13

I haven't tried it, but I brought it to the attention of my father's neurologist who is treating him for Parkinson's.

I read an article (Medscape.com) (Amer Psychiatric Assn Annual Meeting, 5/17/99, Charles Bowden MD) which claimed that Mirapex was added to a variety of AD's, at a dose of .25 mg twice a day, and increased as clinically indicated to a total of .5 and 2.0 mg/day. This resulted in a 40% reduction in depressive symptoms by the end of a four week period. Nausea was experienced by 63% of the patients.

My father is also depressed and I thought that Mirapex could kill two birds with one stone. His doctors have not made any changes in his treatment, but if it were me, I would try it.


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