Posted by sukarno on March 18, 2010, at 3:02:14
In reply to Re: Tianeptine (Stablon) withdrawal symptoms, posted by sukarno on March 18, 2010, at 2:47:32
I wonder why Servier, or another company for that matter, doesn't try to market an extended release formulation of tianeptine.
Servier could extend their patent if they did that and patients might respond a lot better.
The half-life is just too short for it to have a sustained effect. I've heard from at least one other person that it has a "see-saw" effect. It leaves the body too quickly.
Paxil, for example, has a half life of about 20 hours? Stablon's half-life is only 2.5 hours by comparison.
poster:sukarno
thread:798414
URL: http://www.dr-bob.org/babble/wdrawl/20090801/msgs/939904.html