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Re: Lyrica (pregabalin) » KayeBaby

Posted by SLS on July 22, 2006, at 6:34:16

In reply to Re: Lyrica (pregabalin), posted by KayeBaby on July 21, 2006, at 14:10:32

Hi KB.

> I have Non Verbal Learning disorder which looks and acts much like mixed ADD and possibly Biporla II (Hypomanias induced by mosty by meds)
> My depressions are of the atypical sort. Hypersomnia, weight gain with the ability to temporarily pull out.

That's interesting. It was a pet idea of mine that mood reactivity would not be a feature of bipolar disorder. Oh, well.

> I have taken almost all stims available aside from desoxyn. Right now I am on Didrex and Dexedrine spansules 10mg per day.

I might give sibutramine (Meridia) a try soon. It is a drug currently approved for obesity, but was originally developed as an antidepressant. It seems to be effective for fibromyalgia and Tourrettes. Its metabolites seem to be more potent dopamine reuptake inhibitors than Wellbutrin, Effexor, or Cymbalta. It might be an interesting drug for you to investigate.

> I also have an element of post viral fatigue/cfs which clouds the issue somewhat due to some purely biological exhaustion.

Ah. Interesting. Given the association between CFS and fibromyalgia, sibutramine becomes a more attractive drug for you.

Thanks for giving me your impressions of Lyrica. I'll definitely keep it on my list of things to try. I wish it didn't have such a short half-life, though.

I have had weird reactions to mood-stabilizers. They will sometimes give me a brief mild mood lift in the beginning and then leave me feeling flat. Lithium, Neurontin, and Depakote did that. I have been taking Lamictal for a few years. It seems to help a bit when combined with an antidepressant. Right now, Topamax is giving me a slight improvement in mental energy and focus, although it might be fading. It is hard to tell. I am currently taking 125mg. I am thinking that I should work up to 200mg before giving up on it.

Thanks again for your reply. It was very helpful.


- Scott

 

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