Posted by tessellated on February 24, 2006, at 10:12:20
In reply to Re: DISCONTINUATION SYNDROME, posted by SLS on February 24, 2006, at 7:13:40
Valid point!
Kindling as far as i've heard is a synaptic potentiation that requires a lower and lower electrical charge/threshold prior to causing neural excitation.
I've mostly heard about this in regard to epilepsy.
That the more seizures one experiences the more likely they are to occur.
Though I do think it has also applications to bipolar disorder.
Theories on the benefit of inhibiting the swings. Fewer cycles=fewer cycles.Mostly my point was in regard to this "brain damage" chat going on. Brain damage I'd understand as cell death. Yes there are many agents that cause this. However most of the best AD's have gone through relatively rigorous research on rats, cats, dogs, and primates, to determine the possibility of drug induced cell death. However many AD's contribute to neural growth.
So I think most of the AD withdrawl is based on a dysregulation of you neurons, not cell death (when taken appropriately).
I'm not so sure about this when it comes to the issues of the neuroleptics i.e. antipsychotics and the sideeffect of tardive dykinesia. Since this is so common and permanent, it makes me wonder...
Obviously, I suppose I could be totally wrong. I'm just relaying something to take the edge off the word "BRAIN DAMAGE". Cuz if I felt like hell, and heard that word; I'd probably start feelin even worse.
8ted
> I would caution that one does not underestimate the long-term changes that brief exposures to kindling events can produce. If the withdrawal symptoms of a discontinuation syndrome are left to occur unmitigated, my personal belief is that subsequent discontinuations will display a lower threshold in the production of withdrawal symptoms, more intense symptoms, and a syndrome that lasts longer.
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> Is this brain damage?
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> - Scott
poster:tessellated
thread:612630
URL: http://www.dr-bob.org/babble/wdrawl/20060117/msgs/612774.html