Posted by SLS on March 1, 2005, at 9:34:18
In reply to Re: Going Off Klonopin, posted by NealMcCoy on March 1, 2005, at 3:27:21
Hi.
Benzodiazepines act as a sort of key to unlock the door for GABA to open, allowing chloride ions to enter the neuron. Benzodiazepines actually bind to a separate receptor that is intimately connected to the GABA receptor. The interesting thing about this interaction is that GABA can open the door by itself without the benzodiazepine, but it just takes a lot longer. What's more, GABA acts to help the benzodiazepine find the door lock more quickly. In other words, the benzodiazepine molecule and the GABA molecule act synergistically to amplify the GABA neuronal signal. As GABA signals increase, they act to inhibit or "calm down" excitatory neurons.
- Scott
poster:SLS
thread:464665
URL: http://www.dr-bob.org/babble/wdrawl/20050228/msgs/464833.html