Posted by mtdewcmu on January 2, 2010, at 11:34:11
In reply to Re: Which Drug increase dopamine the most? » Phidippus, posted by metafunj on November 2, 2009, at 23:24:59
> http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1448202/
>
> According to this study, in humans methylphenidate is the strongest inhibitor of DAT. If you scroll down to methods you can see they used D-amphetamine. The study shows D-amphetamine blocks more NETs than DATs.
>
> I wonder if Modafinil works more on DAT than NET? Wellbutrin is supposed to be stronger on DAT than NET as well but it felt like just NRI to me based on side effects.Wellbutrin is a stronger blocker of DAT, but if I remember correctly its active metabolite(s) are stronger blockers of NAT and they achieve higher concentrations than the parent drug.
poster:mtdewcmu
thread:924176
URL: http://www.dr-bob.org/babble/neuro/20091104/msgs/932113.html