Posted by linkadge on November 18, 2004, at 19:22:49
In reply to Re: Brain energy and brain disease » linkadge, posted by raybakes on November 18, 2004, at 18:26:53
Have I heard of BDNF ???
I am the king of BDNF research.
I have spent the last year researching any possible supplement/drug/etc that has any effect on the expression of BDNF.
BDNF (brain derived neurotrophic factor) and NGF (nerve growth factor) are two of the foremost growth factors in the brain. Most effective antidepressants increase BDNF. BDNF, and NGF contribute to neuronal differentiation and synaptic repair. I wached a real time video of neurons exposed to the BDNF molecule. THe nerves were just sitting around doing nothing, but when BDNF reached them they started branching out and making connections like crazy (good/bad, who knows)
ECT seems to cause the most acute and robust increase in BDNF (like 150% increase). Exercise and AD medications increase it too, but to lesser extends. (30% )
I found an article today that even suggested that mice exposed to Mozart, had higher levels of BDNF and CREB, compared to mice that listened to white noice.
I base my life on the idea that boosting BDNF, kickstarts hippocampal repair.
Linkadge
poster:linkadge
thread:417331
URL: http://www.dr-bob.org/babble/alter/20041108/msgs/417651.html