Posted by undopaminergic on January 23, 2024, at 10:38:14
In reply to Re: Vortioxetine revisited at 20 mg, posted by SLS on January 8, 2024, at 12:15:36
> Hi.
>Hi SLS!
> Memantine produced no noticeable improvement for me. I'm pretty sure I used the maximum recommended dosage.
>It is my experience and understanding from what I've read, that the initial dose, if sufficient, should make you feel "weird".
My first dose was 10 mg, and I did feel weird, so I did not take more, until weeks or months later, and then it produced a nice antidepressant response, without any "weirdness". I don't recall whether my second dose was 10 or 20 mg.
At a (months) later point, I needed 60 mg, so the maximum recommended dose may not be sufficient. I survived an overdose of several grams (a gram is 1000 mg), so I would not personally worry about taking a couple of 100 mg or so on a regular basis.
> I also chose to add bromocriptine and pergolide (separately) to this combination, as both are DA receptor agonists. Both are available in the U.S. to treat Parkinson's Disease. I experienced a few days of relief before I relapsed.
>Unfortunately, it may not be a good idea to take ergoline-based dopamine agonists in the longer term, as they can produce fibrosis and valvulopathy. Lilly was sued over this.
> Did any of the DA receptor partial agonist antipsychotics have any positive effects on you at all?
>No, they didn't, but I never tried 2.5 mg of aripiprazole (Abilify), only higher doses.
-undopaminergic
poster:undopaminergic
thread:1122281
URL: http://www.dr-bob.org/babble/20230117/msgs/1122308.html