Posted by PeterMartin on April 1, 2022, at 12:17:28
In reply to Re: combining nardil and parnate ) SLS, posted by Lamdage22 on April 1, 2022, at 12:10:47
> Some blood work might be good, too. I think when meds dont work, it could be because nutrients are lacking.
I've learned that a lot of times when meds don't work (or suddenly stop working), it's due to my pharmacy giving me a different generic manufacturer. It's extremely frustrating since most pharmacists/doctors/patients will doubt that there can be any difference. I saw this post on reddit recently about potential for differences between generics (even batches), and found it reassuring since I've noticed but faced skepticism.
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Question/Title of thread:
"Do different manufactures for the same medication really make a difference? Or is that just some my patients like to complain about lol""I know some people prefer the size and shape of specific manufacturers because of issues like cutting the medication in half, or swallowing; but pharmacologically, they are exactly the same, no?"
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Top comment reply:
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"For those whove never worked in manufacturing, I can tell you that regardless of what is being made, the working site / company matters.Drugs would be build to specmeaning they all have the same specs for mixing and chemical composition. But the number of variations in manufacturing are legion: how much tolerance is in equipment used, how frequently do they lubricate bearings, how often do they change dies, how do they get notified of and handle quality errors in production, what humidity and temperature does the mixing happen at, how sensitive is the measuring equipment, where do they get their raw materials from, do they empty their inventory fifo or lifo and what impact does that have on chemical mixing, etc. At one company I worked we even used a pill making machine that we repurposed for a different use because it was designed to handle sensitive powdersand I can tell you there is PLENTY that could vary not only manufacturer to manufacturer, but sure to site within the same manufacturer or even department to department within the same site."
Link for full thread: https://old.reddit.com/r/pharmacy/comments/tpe4nm/do_different_manufactures_for_the_same_medication/
poster:PeterMartin
thread:1119086
URL: http://www.dr-bob.org/babble/20220128/msgs/1119214.html