Posted by linkadge on July 2, 2020, at 17:23:53
In reply to Re: Atomoxetine helping - fingers crossed, posted by PeterMartin on July 1, 2020, at 23:43:14
Yeah, do watch this combination.
Although atomoxetine is (on paper) an NRI, I remember reading that in vivo (in higher doses) it can begin to occupy the serotonin transporter (as the norepinephrine transporter becomes saturated).
There was a study in primates suggesting that in the 1-2 mg/kg range there was a notable inhibition of serotonin transporters.
https://pubmed.ncbi.nlm.nih.gov/23933039/
At 18mg, I don't think there would be an issue, but I would raise the dose more slowly / cautiously beyond that.
Linkadge
poster:linkadge
thread:1110783
URL: http://www.dr-bob.org/babble/20200511/msgs/1111120.html