Posted by linkadge on July 29, 2019, at 19:14:31
In reply to Re: I need some advice regarding my medication regimen » Christ_empowered, posted by Hordak on July 28, 2019, at 16:06:44
Suposedly (in head to head trials) surmontil is as effective for depression as imipramine. This is hard for some to believe, but it may be evidence that there is an additional (yet undiscovered) common mechanism of the TCAs. I remember reading that a metabolite of trimipramine inhibits MAO-B and DAT. Also, like other TCAs is has an indirect effect on opioid systems. However, it is a VERY strong antihistamine (I took 25mg and slept till 4:00 pm the next day).
Honestly, if you were to try one TCA, I would highly recommend clomipramine.
Linkadge
poster:linkadge
thread:1105412
URL: http://www.dr-bob.org/babble/20190728/msgs/1105503.html