Posted by TriedEveryMedication on June 25, 2018, at 14:59:48
my adhd-pi seems to respond to NRIs, especially desipramine.
I've tried atomoxetine which I've seen marketed as a "safer desipramine", but it just doesn't work as well.
the Ki for atomoextine for NET is 5 and for desipramine is like 0.2. (lower the constant, the greater the affinity)
reboxetine isn't available in the US and its binding profile with NET is 13, weaker than atomoxetine.
I guess Protriptyline is an option, its Ki is 1.4. still weaker than desipramine, though.
poster:TriedEveryMedication
thread:1099300
URL: http://www.dr-bob.org/babble/20180521/msgs/1099300.html