Posted by Mark25 on July 25, 2016, at 2:43:03
In reply to Re: MAOI + Trazodone + Olanzapine combination, posted by rjlockhart37 on July 24, 2016, at 23:37:08
Thanks for your answer and the link to the study!
"A case report by Haslett and Kumar noted the development of serotonin syndrome after olanzapine was added to a drug regimen of lithium and citalopram. The mechanism is thought to be 5HT-2A and 5HT-3A receptor antagonism by these atypical antipsychotics, resulting in serotonin accumulation and cumulative activation of 5HT-1A receptors."
Even with this knowledge I still believe MAOI + Olanzapine is safe, especially when you have been on the Olanzapine for quite some time and then slowly add the MAOI:
poster:Mark25
thread:1090832
URL: http://www.dr-bob.org/babble/20160713/msgs/1090845.html