Posted by J Kelly on May 18, 2016, at 23:21:08
In reply to Re: Nardil Insomnia, posted by linkadge on May 18, 2016, at 20:10:00
> Hi,
>
> MAOI insomnia can be nasty. Biochemically, MAOs can increase endogenous tryptamine, which activates 5-ht2a and disrupts sleep and melatonin cycles. I would reduce the dose of nardil (if at all possible) and try augmenting with Seroquel (or other non-serotonergic 5-ht2a blocker).
>
> trimipramine, cyproheptadine perphenazine, or possibly the herb feverfew might work.
>
> I would personally avoid melatonin. I find melatonin doesn't work well with monoamine enhancers. It does mix well with monoamine blockers like remeron, however.
>
> Linkadge
Hello,Perphenazine is a med I was gonna look at. I think its Zyprexa (the poster) that said she has had a good experience with it and I believe she combines the two (Zyprexa and perphenazine).
Any thoughts as to how this med will get along with Zyprexa, klonopin, and Nardi?
I think it has sedative properties and I didn't see weight gain as a side effect. Weight gain and insomnia are both becoming problems.
Thanks for the advice,
Jade
poster:J Kelly
thread:1089052
URL: http://www.dr-bob.org/babble/20160501/msgs/1089073.html