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Lexapro / Wellbutrin combination - dangers?

Posted by tony p on March 29, 2016, at 23:24:11

My pdoc has added Wellbutrin (bupropion) to my Cipralex (Lexapro, escitalopram). I started out on 20 mg Cipralex & 150 mg Wellbutrin, but had to cut back on both (10 mg Cip, 37.5-75 mg Wb) -- I am still trying to find the ideal dose, I'm very sensitive to Wellbutrin.

Recently I checked interactions on RxList and this combination was red-flagged, Wb can elevate escitalopram levels so there is risk of Serotonin Syndrome. On my pharmacist's advice I started checking my blood pressure & pulse, and found that by late afternoon my BP was considerably elevated -- 160+/85+. When I cut my Cipralex from 20 mg/day to 10, my BP dropped noticeably but was still elevated.

My GP checked my BP and found it normal and told me to stop worrying -- obsessing about my BP was probably driving it up! But I'm still concerned. Anyone else have experience with this combo, especially if you're sensitive to stimulants as I am?


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poster:tony p thread:1087645
URL: http://www.dr-bob.org/babble/20160306/msgs/1087645.html