Posted by Hello321 on February 22, 2016, at 0:58:00
In reply to Re: Update on my Diet, posted by Hello321 on February 19, 2016, at 17:55:30
"Both types 1 and 2 diabetes are associated with increased risks of age-related decay in cognitive function and mood disorders, especially depression. Insulin action has been shown to regulate neuronal signaling and plasticity. Here we investigate whether brain-specific knockout of insulin receptor (NIRKO) in mice causes behavioral changes and how these are mechanistically linked. We find that NIRKO mice exhibit age-related anxiety and depressive-like behavior. This is due to altered mitochondrial function, aberrant monoamine oxidase (MAO) expression, and increased dopamine turnover in the mesolimbic system, and can be reversed by treatment with Mao inhibitors. Thus, brain insulin resistance alters dopamine turnover and induces anxiety and depressive-like behaviors. These findings demonstrate a potential molecular link between central insulin resistance and behavioral disorders."
http://m.pnas.org/content/112/11/3463.abstract
Apparently the more sensitive ones insulin receptors, the more their body and brain health benefits. A drug known as Metformin is used to increase The body's insulin sensitivity and has been shown to actually decrease the fundamental effects of aging. Metformin is a lot like the Ketogenic Diet in pill form.
poster:Hello321
thread:1086212
URL: http://www.dr-bob.org/babble/20160131/msgs/1086381.html