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Re: Hypotension, MAOI's, and Moclobemide » chumbawumba

Posted by SLS on September 14, 2015, at 2:06:46

In reply to Re: Hypotension, MAOI's, and Moclobemide, posted by chumbawumba on September 14, 2015, at 1:21:21

> > I believe that:
> >
> > 1. Moclobemide poops-out 90 percent of the time, leading to a constant escalation in dosage to 1200 mg/day without continued relief.
> >
> This was my experience
> >
> >
> > 4. If moclobemide does work for you, it usually does not produce sexual side effects or weight gain.

> This was also my experience.
>
> Great medication, when it worked. Now I'm on Parnate, It's been a week at 20 mg and I already feel a lot better.

Don't forget that Parnate has some amphetamine-like properties. The effects feel pretty good in the beginning, but can wear off quickly. This is usually not the true antidepressant effect, though. That might take a month or more to develop, especially when titrating gradually. Also, most people need a minimum of 40 mg/day. I would say that the range should be between 40 - 80 mg/day. Some people respond only to high-dose therapy; 120 mg/day or more. Although I have heard of people taking 300 mg/day, I have seen studies use a maximum dosage of only 170 mg/day (Jay Amsterdam).

I hope that you have better luck with Parnate than you did with moclobemide.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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