Posted by tiopenster on June 11, 2015, at 15:11:08
In reply to Re: Medications that don't touch the 5HT1 receptor? » tiopenster, posted by phidippus on June 11, 2015, at 14:22:44
I've been on
neurontin (not effective),
depakote (not effective),
lamictal (somewhat effective),
lithium (not effective),
topamax (made me feel depressed)
lyrica (very effective, but poops out after a week)abilify (not effective),
seroquel (akastisia),
geodon (effective, then dropped in effectiveness)
risperdal (not effective)
zyprexa (very effective at over 10mg, but made me gain 45 lbs and very very tired)SSRIs & SNRIs
(all would make me feel perfect the first 2 to 3 days, but then would make me cycle - usually anxiety, normal, manic (only on lexapro), and sometimes depressedLexapro - made me crazy anxious and gave me panic attacks
Serozone - increased anxiety 10 fold
Cymbalta (cycling every few days
Paxil (same pattern)
Zoloft (same pattern)
Nortryptiline (same pattern)
Effexor (felt good immediately, but got a rash)
Buspar (same pattern)Remeron (very effective, - similar to zyprexa. made me gain a lot of weight and turned me into a zombie
The cocktail that resolved my problems 2 years ago was the following, but I was a zombie that slept a lot and didn't talk much
Geodon
Lamictal
Lyrica
Remeron
KlonopinI had gotten off Lamictal, Lyrica & Remeron. I got my geodon to 20mg but kept that dose for insomnia that would come from tapering off Klonopin. My anxiety came back after I had gotten down to .5mg of Klonopin after being on 2mg.
I am doing better on 225mg of lyrica and 50mg of Insidon (german medication). I'm back on 2mg of klonopin and still on 20mg of Geodon. I still need something more - i will most likely go up on the insidon.
The ones I do best on are the ones that don't touch my 5ht1 receptor - remeron and insidon. Zyprexa seems to be weak at the 5ht1a. Lyrics works 100% when i start it but then drops in effectiveness a week later (dose is irrelevant).
Any other suggestions would be great. I have looked at Trimipramine which doesn't touch that receptor either, but makes me incredibly zombie like the next day for anything over 50mg.
poster:tiopenster
thread:1079343
URL: http://www.dr-bob.org/babble/20150520/msgs/1079650.html