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Re: Itching: Temazepam, Parnate or Amitriptyline? » ed_uk2010

Posted by Robert_Burton_1621 on February 17, 2015, at 8:44:03

In reply to Re: Itching: Temazepam, Parnate or Amitriptyline? » Robert_Burton_1621, posted by ed_uk2010 on February 15, 2015, at 13:26:09

> Itching really isn't a common side effect of benzos at all. Given your history, I think you can almost rule it out as the likely cause if you're still itching today... unless you came out in a rash after you took it.
>

No rash. I think you're bang-on. It's not the benzo.

> Some antihistamines are safe with MAOIs and others are not (in no case does the risk of side effects appear to have anything to do with histamine itself). I suggest you try cetirizine 10mg/day, if you haven't already. It's non-prescription in most countries and produces very potent H1 antagonism in the skin. Do not buy chlorphenamine/chlorpheniramine, it's a weak SRI>

Thanks, Ed, that's important advice. I bought some Zyrtec (cetirizine) today

> I've heard of problems when stopping other antihistamine ADs such as mirtazapine. Do you have any allergies or skin problems? If so, amitriptyline may have been suppressing a reaction to something in the environment.
>

No pre-existing allergies or skin problems at all. No other sensitivities. No change in environmental circustances for 12 years. So my tentative conclusion is the ferocious pruritis is not an allergic reaction which the endep was surpressing. It seems that my H1 receptors are going haywire and are hyper-sensitive after having been anatgonised by the endep at high doses. I've tried to find information on this but so far nothing has come up.

> >And the only other possible cause is parnate itself.
>
> It doesn't really correlate.

That is a relief to hear!


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