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Re: lithium and inositol » mogger

Posted by SLS on January 5, 2015, at 4:45:47

In reply to Re: lithium and inositol » mogger, posted by mogger on January 1, 2015, at 22:08:26

Hi Joseph.

> I have one question if you don't mind answering and then I promise I will stop bothering you! When I started 6 years ago inositol my libido dropped adding to all this. I noticed that lithium increases the amount of inositol in the brain? I could be reading the excerpt wrong below but just wonder your thoughts on it. It is from wikipedia. Thanks Scott,

I'm afraid I can't help you out with this one. I am not at all familiar with the functions of inositol in this context. It would seem that lithium inhibits the production of inositol and reduces signal transduction. That's about all I can glean from this information.


- Scott

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> "Lithium treatment has been found to inhibit the enzyme inositol monophosphatase, leading to higher levels of inositol triphosphate.[63] This effect was enhanced further with an inositol triphosphate reuptake inhibitor. Inositol disruptions have been linked to memory impairment and depression.
> In 2014, it was proposed that lithium treatment works by affecting calcium signaling by antagonizing N-methyl-d-aspartate (NMDA) receptors and inhibing inositol monophosphatase (IMP) to synergistically block the inflow of calcium into neurons from both external and internal calcium stores.[64]"


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URL: http://www.dr-bob.org/babble/20150102/msgs/1074814.html