Re: TRK-b agonists for BDNF knockouts

Posted by linkadge on September 15, 2014, at 20:03:59

In reply to Re: TRK-b agonists for BDNF knockouts, posted by linkadge on September 15, 2014, at 19:57:40

BDFN is an interesting target. Enhancement of BDNF signalling interacts with P11 to enhance the surface expression of 5-ht1b receptors. It also can increase reward sensitivity via enhancing dopamine d3 expression. I think there is interaction too with gsk3. I think gsk3 inhibitors can enhance BDNF. I remember reading that ketamine's enhancement of BDNF was abolished if the effect of gsk3 was abolished.
I just have a surface knowledge though.
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BDNF gene predicts the response to ketamine SLS 9/14/14
Re: BDNF gene predicts the response to ketamine linkadge 9/14/14
Re: BDNF gene predicts the response to ketamine Lamdage22 9/14/14
Re: BDNF gene predicts the response to ketamine » linkadge SLS 9/14/14
Re: BDNF gene predicts the response to ketamine » SLS Phillipa 9/14/14
Re: BDNF gene predicts the response to ketamine » Phillipa SLS 9/14/14
Re: BDNF gene predicts the response to ketamine » SLS Phillipa 9/14/14
Re: BDNF gene predicts the response to ketamine Lamdage22 9/14/14
Re: TRK-b agonists for BDNF knockouts linkadge 9/15/14
Re: TRK-b agonists for BDNF knockouts SLS 9/15/14
Re: TRK-b agonists for BDNF knockouts linkadge 9/15/14
Re: TRK-b agonists for BDNF knockouts linkadge 9/15/14

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