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Re: Best dopamine enhancing selective med

Posted by Sugardog on July 9, 2014, at 23:31:09

In reply to Re: Best dopamine enhancing selective med » Sugardog, posted by phidippus on July 9, 2014, at 21:16:29

> > I'd really appreciate some advice.
> > I'm currently on 20mgs Lexapro
>
> In order to treat your OCD and depression effectively, you really need to be on a higher dose of Lexapro - I'd recommend you increase the dose to 4o mg (but have an EKG done to check for QT prolongation).
>
> OCD involves lowered levels of serotonin in certain regions of the brain but also raised levels of dopamine in other regions, most importantly the nucleus accumbens. A strategy used to treat these imbalances is to prescribe an atypical antipsychotic to augment treatment with an antidepressant. Two atypicals may be of interest to you which may help with your depression and your OCD: Latuda and Geodon.
>
> > The Adderall calms my mind but doesn't make me feel good, productive, social, or focused.
>
> This response indicates to me that you probably don't have ADHD, but thAT the adderall is helping with your OCD (studies suggest dextroamphetamine can treat OCD) which is why your mind feels calmer.
>
> > I'm very interested in finding a medication that selectively targets dopamine and doesn't increase norepinephrine.
>
> There are two drugs that increase dopamine: Mirapex and Requip, but a possible side effect of those drugs is an increase in addictive behaviors.
>
> I would recommend you drop the adderall and add Latuda or Geodon either of which can potentially help with your depression and OCD.
>
> Any questions?
>
> Eric
>
Dear Eric,

Really interesting thoughts. Thank you!! It hadn't occurred to me that the calming response to Adderall my be linked to OCD.

I was on 40mgs of Lexapro years ago, which helped with my energy and depression but strangely increased my impulsiveness and poor judgement.

I'll definitely bring up the other meds you recommended to my pdoc. I haven't tried any of them yet.

Again, thank you. I'm really determined to find a solution right now. I've been struggling since my teen years.


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URL: http://www.dr-bob.org/babble/20140609/msgs/1068152.html