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Re: Scott, can you enlighten me? (Nmda) » Lamdage22

Posted by SLS on November 17, 2013, at 10:08:01

In reply to Scott, can you enlighten me? (Nmda), posted by Lamdage22 on November 16, 2013, at 11:45:37

> Scott,
>
> how is it that sarcosine and glycine are good for schizophrenia as agonists and at the same time minocycline and lamictal are good as antagonists.

I am not educated enough to answer your question.

When glycine bonds to its sub-receptor of the NMDA receptor, it acts to reduce excess glutamateric activity. Minocycline and Lamictal reduce excess glutamatergic activity as well, albeit through different mechanisms.

Sorry I couldn't help you with the sarcosine.

- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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URL: http://www.dr-bob.org/babble/20131115/msgs/1054529.html