Posted by SLS on November 17, 2013, at 10:08:01
In reply to Scott, can you enlighten me? (Nmda), posted by Lamdage22 on November 16, 2013, at 11:45:37
> Scott,
>
> how is it that sarcosine and glycine are good for schizophrenia as agonists and at the same time minocycline and lamictal are good as antagonists.I am not educated enough to answer your question.
When glycine bonds to its sub-receptor of the NMDA receptor, it acts to reduce excess glutamateric activity. Minocycline and Lamictal reduce excess glutamatergic activity as well, albeit through different mechanisms.
Sorry I couldn't help you with the sarcosine.
- Scott
Some see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1054471
URL: http://www.dr-bob.org/babble/20131115/msgs/1054529.html