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Re: Irving Kirsch, placebos and antidepressants » larryhoover

Posted by doxogenic boy on November 11, 2013, at 12:06:25

In reply to Re: Irving Kirsch, placebos and antidepressants » doxogenic boy, posted by larryhoover on November 9, 2013, at 12:50:16

Thank you very much for your thoughts about this. I have now read your three posts from alt.support.depression.medication too. I used to read that newsgroups about ten years ago, but last time I checked, it was dead.

I have found a meta analysis in fulltext in Canadian Medical Association Journal:

http://www.cmaj.ca/content/178/3/296.long

Excerpt from article:
Effectiveness of paroxetine in the treatment of acute major depression in adults: a systematic re-examination of published and unpublished data from randomized trials

Corrado Barbui MD,
Toshiaki A. Furukawa MD,
Andrea Cipriani MD

[...]
Interpretation: Among adults with moderate to severe major depression in the clinical trials we reviewed, paroxetine was not superior to placebo in terms of overall treatment effectiveness and acceptability. These results were not biased by selective inclusion of published studies.
End quote.
------------------------
Have you seen this article before, and what do you think about it?

I found the meta analysis in the references list of this article:
http://tidsskriftet.no/article/3001711/en_GB
I have met O.B. Fasmer (one of the authors) once as a patient.

- doxogenic


Earlier TRD/anxiety
300 mg tianeptine, 6 X 50 mg successfully since Oct 2009
20 mcg liothyronine
40 mg escitalopram
100 mg trimipramine
50 mg agomelatine
600 mg quetiapine


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URL: http://www.dr-bob.org/babble/20131025/msgs/1054138.html