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Re: new antidepressant mechanism » linkadge

Posted by SLS on October 29, 2013, at 20:46:34

In reply to Re: new antidepressant mechanism, posted by linkadge on October 29, 2013, at 19:03:52

> Its not really a *new* mechanism. Some antidepressants already interact with the 5-ht2c receptor (i.e. trazodone, mirtazapine, minaserin, TCA etc.)
>
> Linkadge


I think that it is the specificity (rather than selectivity) for the serotonin 5-HT2c receptor that is what is claimed to be the novel property of this drug. It shouldn't affect other 5-HT receptors at all. Is it possible that antagonism of other serotonin receptors counter the antidepressant effects of 5-HT2c antagonism?


- Scott

Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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poster:SLS thread:1053317
URL: http://www.dr-bob.org/babble/20131025/msgs/1053355.html