Posted by SLS on April 27, 2013, at 9:14:03
In reply to Schizo affective going off meds., posted by Danielj on April 26, 2013, at 21:31:23
> My son's Pdoc agreed to try a while off medications. Right now he is a litle better off meds than he was on them. 7 years of Zyprexa and Zoloft every day then a few tries of different meds like Latuda and Saphris and back on Zyprexa the past month with no real success. He seems to function normally except for binge buying and eating occasionally which are part of his Schizo affective anyway. This will be kind of a detox period. What do you think?
Zoloft can be numbing (cognitively) and produce apathy and perhaps "brain-fog". People can react differently to the same medication. Some people experience a "clean" antidepressant effect from Zoloft without the numbing and apathy. Sometimes, trial-and-error is a necessary component to choosing medications. Your son might be feeling somewhat better for having discontinued the Zoloft, as any numbing effect may have dissipated.
Discontinuing Zyprexa might produce significant anxiety. Sometimes, this is due to what is known as a rebound effect. If the anxiety is a rebound phenomenon, it should be temporary, but may still warrant intervention - perhaps by using an anxiolytic drug for a brief period of time. If anxiety was a feature of the original illness (baseline), this might be a sign of relapse, in which case it would not be temporary. In any event, your son should be closely monitored to screen for changes in symptoms and mood. Discontinuing both Zyprexa and Zoloft could produce a rebound depression that, although temporary, may be severe enough to produce suicidal thoughts.
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