Posted by Tyrannosaur on April 12, 2013, at 1:15:18
In reply to Re: PARNATE high-dose strategy and diminishing returns, posted by vanvog on April 11, 2013, at 22:04:26
> I'm familiar with the concept of diminishing returns, I would however like to know what made those people who pursued a high-dose strategy stop upping the dose. Let's say I get a 10% (or 5%) improvement on my symptom(s) by pushing the dose another 20mg further, I would do it if cost is no concern and the side-effects don't get worse by doing so.
Perhaps those people accidentally read this;
"Tranylcypromine
- >1 mg/kg associated with toxicity
- 170 mg has caused a fatality"http://curriculum.toxicology.wikispaces.net/Monoamine+oxidase+inhibitors+%28Detail%29
"More than 1 mg/kg is likely to be a significant poisoning"
Pursuing symptom relief from very high doses might produce the opposite effect. But people have done it before, although would being on very high doses of TCP long-term be a viable option?
Just be careful and be well.
poster:Tyrannosaur
thread:1042019
URL: http://www.dr-bob.org/babble/20130408/msgs/1042070.html