Posted by bleauberry on March 3, 2013, at 11:59:40
In reply to Why would someone be immune to stimulants?, posted by joe schmoe on March 1, 2013, at 6:55:49
Dopamine receptors can become oversensitive, undersensitive, and genetics can cause them to start the game one way or the other. Insults from disease, inflammation, drugs, and meds can change those sensitivities, and once they are changed we are in no man's land, a place of mystery far beyond human comprehension.
To make it more confounding, there are many different types of dopamine receptors, and they all play various roles, and they are located in various regions of the brain. It's almost like trying to figure out a puzzle with blind folds on.
I do not believe your questions have useable answers. Theoretical answers yes. Whether that turns into clinical usefulness is doubtful.
Effexor is playing a role in this, maybe making some things a little better and other things worse.
Experimentation with stuff is the only way to find out what is going to help or not. And I would strongly suggest venturing outside the small limited box of psychiatry to find other ideas.
Approaches such as anti-inflammation, anti-microbial, and anti-toxin, as well as careful choice of foods in the grocery cart, all make more of a difference than people realize. Sometimes even cure. But almost always at least helpful.
I have seen, right here at babble, remission happen after decades of failed meds, by things as simple and basic as.....going gluten free....diagnosing a sleep apnea problem....suspecting lyme disease....and such.
poster:bleauberry
thread:1039146
URL: http://www.dr-bob.org/babble/20130222/msgs/1039434.html