Posted by SLS on December 20, 2012, at 23:16:31
In reply to Ketamine- any indicators of who might respond?, posted by alchemy on December 20, 2012, at 22:28:52
> Maybe this is just the latest fad. I think i can finally actually go in for infusions. My excitement has dwindled when reading more studies and experiences. But i like that it works differently than other med approaches. Nmda receptors, glutamate...actually i dont remember. Does anyone have or know of any theories about what type of depression might be more responsive? Or maybe looking at how previous meds affected someone?
That's a great approach.
I don't know the answer to your questions. However, if you respond partially to Lamictal, you might consider trying other anti-glutamatergic drugs before hunting down a facility that offers ketamine infusions. You might want to explore adding minocycline, memantine, or N-acetylcysteine (NAC). Besides, with ketamine infusions, it seems that you need to repeat the procedure to maintain an antidepressant response. The addition of minocycline to my treatment regime produced a more robust antidepressant response for me than the other two drugs I suggested. I am a partial responder to Lamictal.
For what it may be worth, I have seen someone with chronic depression who experienced a partial response to a combination of Lamictal and Abilify achieve remission after adding minocycline. This person does not take any standard antidepressants.
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1033418
URL: http://www.dr-bob.org/babble/20121217/msgs/1033422.html